Drug Class: Third-Generation Cephalosporin Antibiotic | Form: Intravenous (IV) Injection | Prescription Status: Prescription Only (Rx) — DRAP Registered
What is Oxidil 1g IV Injection?
Oxidil 1g IV Injection contains Ceftriaxone Sodium, a strong antibiotic given directly into a vein (نس میں انجیکشن). It belongs to the cephalosporin family and is used in hospitals and clinical settings to treat severe bacterial infections (شدید بیکٹیریل انفیکشن) that need fast, powerful treatment. Because it is given intravenously, it acts quickly and reaches high levels in the blood and body tissues. This injection must always be administered by a trained doctor or nurse in a clinical setting.
What is Oxidil 1g IV Injection Used For?
Oxidil 1g IV Injection is approved for the treatment of the following conditions:
- Lower respiratory tract infections — including severe pneumonia (پھیپھڑوں کا شدید انفیکشن)
- Meningitis — serious infection of the membranes surrounding the brain and spinal cord
- Urinary tract infections (UTIs) — including kidney infections caused by bacteria
- Skin and soft tissue infections — serious wound or skin infections requiring hospital treatment
- Bone and joint infections — bacterial infections affecting bones or joints
- Intra-abdominal infections — infections inside the abdomen, including peritonitis
- Septicaemia — bacterial infection in the bloodstream (خون میں انفیکشن)
- Surgical prophylaxis — administered before surgery to prevent post-operative infection
How Does Oxidil 1g IV Injection Work?
Ceftriaxone Sodium works by blocking the bacteria's ability to build their outer protective wall. Without this wall, bacteria cannot survive and die off. Since it targets bacteria directly and does not affect human cells in the same way, it is effective against a wide range of harmful bacteria. The IV route means the medicine enters the bloodstream immediately, making it especially suitable for severe or life-threatening infections that need urgent treatment.
Dosage and Administration
⚠️ This injection is given only in a hospital or clinical setting by a qualified doctor or nurse. Never attempt self-administration.
| Condition | Usual Adult Dose | Frequency |
|---|---|---|
| General severe infections | 1g – 2g | Once daily |
| Meningitis | 2g – 4g | Once daily |
| Surgical prophylaxis | 1g | Single dose before surgery |
| Septicaemia | 2g | Once daily |
| Severe UTI / kidney infection | 1g – 2g | Once daily |
- Administered as a slow intravenous (IV) infusion or injection into a vein
- The dose and duration of treatment are decided by your doctor based on the type, location, and severity of the infection
- Always complete the full prescribed course — do not stop early even if you feel better
- In children and newborns, dosing is calculated by body weight — the doctor will determine the correct dose
Active Ingredient
| Ingredient | Strength per Vial |
|---|---|
| Ceftriaxone Sodium (equivalent to Ceftriaxone) | 1g (1000mg) |
Who Should NOT Use Oxidil 1g IV Injection?
Do not use this injection if you:
- Are allergic to ceftriaxone, any other cephalosporin antibiotic, or penicillin
- Have a history of severe allergic reaction (anaphylaxis) to any beta-lactam antibiotic
- Are a premature or full-term newborn receiving calcium-containing IV solutions — this combination can be life-threatening
- Have been specifically advised by your doctor to avoid this medicine
Tell your doctor before use if you have any of the following:
- Kidney or liver disease
- History of digestive problems caused by antibiotics (such as colitis)
- Gallbladder disease
- Are pregnant or breastfeeding
Side Effects
Like all medicines, Oxidil 1g IV Injection can cause side effects. Not everyone will experience them.
Common Side Effects:
- Pain, warmth, or swelling at the injection site or along the vein
- Diarrhoea (دست) or loose stools
- Nausea or stomach discomfort
- Skin rash or itching
- Headache
Serious Side Effects — Seek Immediate Medical Attention:
- Severe allergic reaction — sudden rash, swelling of the face, lips, or throat, difficulty breathing or swallowing
- Severe or bloody diarrhoea — may indicate a serious gut infection (C. difficile)
- Yellowing of the skin or eyes (یرقان / jaundice) — possible sign of liver or gallbladder problem
- Reduced urination, leg swelling — possible sign of kidney problem
- Unusual bruising or bleeding — possible effect on blood clotting
- Fits or seizures — particularly in patients with meningitis or kidney disease
If you or someone near you experiences any of these serious effects, go to the nearest emergency department immediately.
Drug and Food Interactions
Always inform your doctor about every medicine you are currently taking before receiving this injection.
| Medicine / Substance | Possible Interaction |
|---|---|
| Calcium-containing IV solutions | Must NEVER be mixed or given together — can cause dangerous deposits in the lungs and kidneys |
| Blood thinners (e.g., Warfarin) | Ceftriaxone may increase bleeding risk — close monitoring required |
| Aminoglycoside antibiotics (e.g., Gentamicin, Amikacin) | Increased risk of kidney damage — use only under close supervision |
| Oral contraceptives (birth control pills) | Antibiotic use may reduce effectiveness — discuss with your doctor |
| Other antibiotics | May affect each other's action — inform your doctor of all medicines |
There are no specific food interactions for IV Ceftriaxone, but always give your doctor or pharmacist a full list of all medicines, supplements, and herbal products you are using.
Storage Instructions
- Store unopened vials below 25°C in a cool, dry place
- Protect from direct sunlight and moisture
- Keep out of reach of children (بچوں کی پہنچ سے دور رکھیں)
- Once prepared (reconstituted), use immediately — discard any remaining solution; do not store for later use
- Do not use after the expiry date printed on the vial or box
Frequently Asked Questions (FAQs)
What is the difference between Oxidil IM Injection 500mg and Oxidil 1g IV Injection?
Both contain Ceftriaxone but differ in dose and route of administration. The 500mg is given into the muscle (IM) and is used for moderate infections. The 1g IV is given directly into a vein and is used for more severe infections that need faster, higher-dose treatment in a hospital setting.
How quickly does Oxidil 1g IV Injection start working?
Because it is given directly into the bloodstream, it begins working almost immediately. Patients often notice improvement within 24 to 72 hours, but it is essential to complete the full prescribed course as instructed by your doctor.
Can Oxidil 1g IV Injection be given to children?
Yes, it can be used in children and even newborns, but only under strict medical supervision. The dose is carefully calculated based on the child's weight and age. Premature or newborn babies receiving calcium IV drips must NOT receive this injection — the doctor will assess safety before use.
Is it safe to use during pregnancy?
Ceftriaxone should only be used during pregnancy if your doctor decides the benefit clearly outweighs any potential risk. Always tell your doctor if you are pregnant, planning a pregnancy, or breastfeeding before receiving any antibiotic injection.
Why must I complete the full course of treatment?
Stopping the antibiotic early — even if you feel better — can leave some bacteria alive. These surviving bacteria can multiply again, cause the infection to return, and may become resistant to antibiotics, making future treatment more difficult.
Can Oxidil IV Injection be mixed with other IV drips?
No. Oxidil 1g IV Injection must never be mixed with calcium-containing IV solutions such as Ringer's Lactate or Hartmann's solution. It should only be prepared and administered by trained medical staff following proper clinical guidelines.
⚕️ Medical Disclaimer: This product description is for general informational purposes only and does not replace professional medical advice, diagnosis, or treatment. Always consult a qualified doctor or pharmacist before using any prescription medicine. This product is available on prescription only and must be administered under the supervision of a licensed healthcare professional.
DRAP Registered | Prescription Required (Rx) | For hospital and clinical use under medical supervision only.