Neurobion Injection (Vitamins B1, B6 & B12)

Product Class: Therapeutic Vitamin B Complex | Form: Intramuscular (IM) / Intravenous (IV) Injection | Prescription Status: Prescription Only (Rx) — DRAP Registered

What is Neurobion Injection?

Neurobion Injection is a combination of three essential B vitamins — Vitamin B1 (Thiamine), Vitamin B6 (Pyridoxine), and Vitamin B12 (Cyanocobalamin) — delivered in a single injection. These three vitamins work together to support the health and proper functioning of the nervous system (اعصابی نظام). When the body is severely deficient in these vitamins, nerves can become damaged or stop working correctly, leading to pain, weakness, and numbness in different parts of the body.

Neurobion Injection is used when oral vitamin supplements are not sufficient — for example, in severe deficiencies, nerve damage conditions, or when the body cannot absorb vitamins properly through the digestive system. It is given as an injection into the muscle (IM) or directly into a vein (IV) by a trained healthcare professional.

What is Neurobion Injection Used For?

Neurobion Injection is prescribed for the following conditions:

• Severe Vitamin B1, B6, and B12 deficiency — when oral supplements are insufficient or the body cannot absorb vitamins through food (وٹامن کی شدید کمی)
• Peripheral neuropathy — damage to the nerves outside the brain and spinal cord, causing pain, tingling, or numbness in the hands and feet
• Diabetic neuropathy — nerve damage caused by long-term high blood sugar levels in diabetic patients (ذیابیطس کی وجہ سے اعصابی نقصان)
• Trigeminal neuralgia — severe shooting pain in the face caused by nerve irritation
• Sciatica — pain running from the lower back down through the leg along the sciatic nerve (سائیٹک اعصاب کا درد)
• Nerve regeneration support — to help damaged nerves heal and recover their normal function
• Neuropathic pain — burning, stabbing, or electric shock-like pain caused by nerve damage or dysfunction
• Alcoholic neuropathy — nerve damage caused by long-term excessive alcohol consumption leading to B vitamin depletion
• Post-surgical nerve recovery — supporting nerve healing after surgical procedures

How Does Neurobion Injection Work?

Each of the three vitamins in Neurobion Injection plays a specific and important role in keeping the nervous system healthy:

Vitamin B1 (Thiamine — 100mg) is essential for producing energy in nerve cells. It helps nerves generate the energy they need to transmit signals properly. A deficiency in B1 can cause serious nerve and brain damage. Delivering it by injection ensures it reaches the nervous system quickly and in full concentration.

Vitamin B6 (Pyridoxine — 100mg) is involved in the production of neurotransmitters — the chemical messengers that nerves use to communicate with each other and with the brain. It also plays a role in forming the myelin sheath, the protective covering around nerve fibres that allows signals to travel efficiently.

Vitamin B12 (Cyanocobalamin — 1000mcg) is the most critical vitamin for nerve health. It is essential for maintaining and repairing the myelin sheath around nerves. Without sufficient B12, nerves lose their protective covering, leading to pain, numbness, weakness, and permanent damage if left untreated. The injectable form ensures maximum absorption — particularly important in patients whose digestive systems cannot absorb B12 from food or oral tablets.

Together, these three vitamins support nerve repair, reduce neuropathic pain, and help restore normal nerve function.

Dosage and Administration

⚠️ Neurobion Injection must be administered by a qualified doctor or nurse. Do not attempt self-injection at home unless specifically instructed and trained by your doctor.

• For IM injection: given as a deep injection into a large muscle, usually the upper arm or buttock
• For IV injection: given as a slow injection into a vein by a nurse or doctor in a clinical setting
• The dose and duration of treatment are decided by your doctor based on the severity of deficiency and your clinical response
• Treatment duration can range from a few weeks to several months depending on the condition being treated

Active Ingredients

Who Should NOT Use Neurobion Injection?

Do not use this injection if you:

• Are allergic to Thiamine, Pyridoxine, Cyanocobalamin, or any other ingredient in the formulation
• Have had a previous allergic reaction to any B vitamin injection
• Have been specifically advised by your doctor not to use this product

Always inform your doctor before use if you have any of the following:

• Kidney disease — B vitamins are excreted through the kidneys; impaired function may require monitoring
• Leber's disease (a rare inherited eye condition) — Vitamin B12 in the form of Cyanocobalamin is not recommended in this condition
• Low potassium levels (hypokalaemia) — B12 treatment can cause a further drop in potassium in some patients
• Polycythaemia vera (a blood disorder) — B12 can worsen this condition
• Are pregnant or breastfeeding — inform your doctor before use

Side Effects

Neurobion Injection is generally well tolerated by most patients. However, like all injectable medicines, side effects are possible.

Common Side Effects:

• Pain, redness, or mild swelling at the injection site
• Mild skin rash or itching
• Nausea or stomach discomfort
• Feeling of warmth or flushing after IV administration
• Mild dizziness

Serious Side Effects — Seek Medical Attention Immediately:

• Severe allergic reaction — sudden rash, swelling of the face, lips, or throat, difficulty breathing (this is rare but can occur, particularly with IV Thiamine)
• Nerve pain worsening with long-term high-dose B6 — prolonged use of high doses of Vitamin B6 (Pyridoxine) can paradoxically cause nerve damage; always follow prescribed duration
• Rapid heartbeat or chest tightness — particularly with fast IV administration
• Severe drop in potassium levels — may cause muscle weakness or irregular heartbeat in some patients starting B12 therapy
• Acne-like skin eruptions — associated with high-dose B12 in some patients

If any serious side effect occurs, inform your doctor immediately or go to the nearest emergency department.

Drug Interactions

Inform your doctor about all medicines you are currently taking before receiving Neurobion Injection.

Storage Instructions

• Store unopened ampoules below 25°C in a cool, dry place
• Protect from direct sunlight and heat — B vitamins are sensitive to light
• Keep out of reach of children (بچوں کی پہنچ سے دور رکھیں)
• Do not freeze
• Do not use if the solution has changed colour, appears cloudy, or contains visible particles
• Do not use after the expiry date printed on the ampoule or outer pack

Frequently Asked Questions (FAQs)

 Why is Neurobion given as an injection instead of tablets?

 In cases of severe deficiency or nerve damage, the body needs much higher and faster concentrations of B vitamins than tablets can provide. Additionally, some patients — particularly those with digestive problems, alcoholism, or certain medical conditions — cannot absorb B vitamins properly through the gut. Injection bypasses the digestive system entirely and delivers vitamins directly into the bloodstream or muscle, ensuring full and immediate absorption.

 How long does it take for Neurobion Injection to work?

Many patients notice a reduction in nerve pain and tingling within a few days to two weeks of starting injections. However, nerve regeneration is a slow process — full recovery of nerve function, particularly in conditions like diabetic neuropathy or peripheral neuropathy, may take several weeks to months of consistent treatment. Your doctor will review your progress and adjust the treatment plan accordingly.

 Can diabetic patients use Neurobion Injection safely?

 Yes, Neurobion Injection is commonly prescribed for diabetic neuropathy (ذیابیطسی اعصابی نقصان). It does not affect blood sugar levels directly. However, diabetic patients on Metformin are especially likely to have B12 deficiency, making this injection particularly beneficial. Always inform your doctor about all your medications so the treatment plan can be tailored safely.

 Can Neurobion Injection be used long-term?

Short to medium-term use under medical supervision is common and generally safe. However, long-term use of high-dose Vitamin B6 (Pyridoxine) can paradoxically cause nerve damage in some patients. Your doctor will monitor your response and determine the appropriate duration of treatment for your condition.

 Is Neurobion Injection safe during pregnancy?

 B vitamins are essential nutrients and are generally considered safe during pregnancy at recommended doses. However, the injectable high-dose form should only be used during pregnancy when clearly needed and prescribed by a doctor. Always inform your doctor if you are pregnant or breastfeeding before receiving any injection.

 Can Neurobion Injection be taken alongside oral Vitamin B supplements?

 This depends on your total daily intake across all sources. Taking both injectable and oral high-dose B vitamins simultaneously without medical guidance may result in excessive intake — particularly of B6. Always let your doctor know about all supplements you are taking so they can advise whether both are necessary.

⚕️ Medical Disclaimer: This product description is provided for general informational purposes only and does not replace professional medical advice, diagnosis, or treatment. Always consult a qualified and licensed doctor or pharmacist before starting, stopping, or changing any medicine or supplement. Neurobion Injection should be used under the guidance of a licensed healthcare professional.

DRAP Registered | Prescription Required (Rx) | Administer under medical supervision only