Drug Class: Beta-1 Selective Adrenergic Blocker | Form: Tablet | Prescription Status: Prescription-Only (Rx) — DRAP Registered
What is Nebivolol 5mg?
Nebivolol 5mg is a prescription beta-blocker tablet containing Nebivolol Hydrochloride 5mg, used to treat high blood pressure (ہائی بلڈ پریشر) and stable chronic heart failure. Nebivolol is a highly selective beta-1 adrenergic receptor blocker that slows the heart rate, reduces the force of heart contractions, and widens blood vessels to lower blood pressure and improve blood flow. Unlike older beta-blockers, Nebivolol also promotes vasodilation through nitric oxide release, making it particularly well tolerated. It is used alone or alongside other medicines to reduce the risk of heart attack, stroke, and cardiovascular complications.
What is Nebivolol 5mg Used For?
Hypertension: Treats high blood pressure in adults to reduce the risk of heart attack, stroke, and other cardiovascular events. Stable Chronic Heart Failure: Used alongside other heart failure therapies to manage mild to moderate stable heart failure, particularly in patients above 70 years of age. Cardiovascular Risk Reduction: Helps protect the heart and blood vessels by reducing cardiac workload and maintaining controlled blood pressure over time.
How Does Nebivolol 5mg Work?
Nebivolol selectively blocks beta-1 adrenergic receptors in the heart, reducing the effect of adrenaline on the heart muscle. This slows the heart rate and reduces the force of each heartbeat, lowering the amount of work the heart has to do. Nebivolol also stimulates the release of nitric oxide from blood vessel walls, causing vasodilation and further reducing blood pressure. This dual mechanism of cardiac slowing and blood vessel widening makes Nebivolol effective for both hypertension and heart failure management.
Dosage and Administration
| Situation | Dose | Frequency |
|---|---|---|
| Hypertension | 1 tablet (5mg) | Once daily |
| Stable chronic heart failure | Starting dose as directed by doctor | Once daily, titrated gradually |
| As prescribed | Follow doctor's instructions | Do not stop without medical advice |
Take with or without food at the same time each day. Never stop this medicine suddenly as abrupt discontinuation can worsen heart conditions. Your doctor will gradually reduce the dose if treatment needs to be stopped.
Active Ingredient
| Ingredient | Role |
|---|---|
| Nebivolol Hydrochloride 5mg | Beta-1 selective blocker — slows heart rate, reduces cardiac workload, and promotes vasodilation to lower blood pressure |
Allergen Warning: These tablets contain lactose monohydrate. Patients with lactose intolerance or galactose intolerance should inform their doctor before use.
Who Should NOT Use Nebivolol 5mg?
Do not use if you have severe heart failure, heart block, very slow heart rate, severe liver disease, severe asthma, or a known allergy to Nebivolol. Tell your doctor if you have diabetes, kidney disease, thyroid problems, or peripheral vascular disease. Inform your doctor if you are pregnant or breastfeeding.
Side Effects
Common: Headache, dizziness, fatigue, slow heart rate, cold hands and feet, nausea. Serious (seek immediate help): Severely slow heart rate or irregular heartbeat, significant worsening of breathlessness or heart failure symptoms, severe allergic reaction including skin rash or facial swelling.
Storage
Store below 25°C in a dry place away from direct sunlight and moisture. Keep out of reach of children (بچوں کی پہنچ سے دور رکھیں). Do not use after the expiry date. Store in original packaging.
Frequently Asked Questions
Can I stop taking Nebivolol 5mg if I feel better?
No. Never stop Nebivolol 5mg suddenly without consulting your doctor. Abrupt discontinuation of beta-blockers can cause a rebound increase in blood pressure, angina, or worsening heart failure. Your doctor will guide you on how to reduce the dose gradually if needed.
Does Nebivolol 5mg affect blood sugar levels?
Nebivolol may mask some symptoms of low blood sugar such as a fast heartbeat, making it harder for diabetic patients to recognise hypoglycaemia. Monitor your blood sugar more frequently when starting this medicine and inform your doctor if you notice unusual changes.
Medical Disclaimer: This description is for informational purposes only and does not replace professional medical advice. Always follow your doctor's prescription and consult your pharmacist for personal guidance.
DRAP Registered | Prescription Required (Rx) | Hypertension and Heart Failure | Beta-Blocker