Drug Class: NSAID (Non-Steroidal Anti-Inflammatory Drug) | Form: Oral Tablet | Prescription Status: Prescription Only (Rx) — DRAP Registered
What is Acenac 100mg Tablet? Acenac 100mg contains Aceclofenac — an NSAID that relieves pain and reduces swelling by blocking the chemicals responsible for inflammation. It is prescribed for joint and musculoskeletal conditions where ongoing pain and stiffness significantly affect daily life. Aceclofenac is generally considered to have a better stomach tolerability profile compared to some older NSAIDs, though stomach protection is still recommended. Always take under medical supervision at the lowest effective dose for the shortest time necessary.
What is Acenac 100mg Used For?
- Rheumatoid arthritis — painful swelling of joints (ریمیٹائیڈ گٹھیا)
- Osteoarthritis — joint wear and pain, especially knees and hips (جوڑوں کا درد)
- Ankylosing spondylitis — inflammatory back and spine stiffness (ریڑھ کی ہڈی کا درد)
- Acute musculoskeletal pain — muscle and joint injuries (پٹھوں اور جوڑوں کا درد)
- Dental pain with inflammatory component (دانت کا درد)
How Does it Work? Aceclofenac inhibits COX-1 and COX-2 enzymes, blocking prostaglandin production at the site of inflammation. Reduced prostaglandins mean less pain receptor sensitisation, less swelling, and lower fever. It also partially converts to Diclofenac in the body, contributing additional anti-inflammatory activity.
Dosage and Administration
⚠️ Always take with food. Never exceed prescribed dose. Avoid combining with other NSAIDs or Aspirin above 75mg.
| Indication | Usual Adult Dose | Frequency | Maximum Daily Dose |
|---|---|---|---|
| Arthritis / Joint pain | 100mg | Twice daily | 200mg per day |
| Acute musculoskeletal pain | 100mg | Twice daily | 200mg per day |
Active Ingredients
| Ingredient | Strength |
|---|---|
| Aceclofenac | 100mg |
Who Should NOT Take Acenac 100mg?
- Allergy to Aceclofenac, Diclofenac, Aspirin, or any NSAID
- Active stomach ulcer or gastrointestinal bleeding
- Severe heart failure or established cardiovascular disease
- Severe kidney or liver disease
- Third trimester of pregnancy
- Children under 18 years of age
- Aspirin-sensitive asthma
Side Effects
Common: Nausea, stomach discomfort, indigestion, mild headache, dizziness — reduced by always taking with food.
Serious — Stop and seek emergency help immediately: Dark or black tarry stools or vomiting blood (پیٹ سے خون — فوری مدد لیں), severe stomach pain, yellowing of skin or eyes (یرقان), chest pain or sudden breathlessness, significant ankle swelling, worsening of asthma after taking tablet, severe skin blistering or peeling.
Drug Interactions
| Medicine | Interaction |
|---|---|
| Other NSAIDs or Aspirin above 75mg | Greatly increased gastrointestinal bleeding risk — never combine |
| Warfarin / blood thinners | Increased bleeding risk — INR monitoring required |
| Antihypertensives (ACE inhibitors, ARBs) | Aceclofenac reduces their blood pressure lowering effect |
| Methotrexate | Aceclofenac increases Methotrexate toxicity — avoid |
| Lithium | Aceclofenac increases Lithium blood levels |
| Corticosteroids (Prednisolone) | Increased risk of stomach ulcers and bleeding |
| Diuretics | Reduced diuretic effect and increased kidney stress |
Storage: Store below 25°C in a cool, dry place. Protect from moisture and sunlight. Keep out of reach of children (بچوں کی پہنچ سے دور رکھیں). Do not use after expiry date.
FAQs
Q: Can I take Acenac 100mg for long-term arthritis management? Acenac can be used long-term under doctor supervision, but regular monitoring of kidney function, blood pressure, and stomach health is essential to avoid serious complications.
Q: Is Acenac safe to take without food? No — always take with food or immediately after a meal. Taking on an empty stomach significantly increases the risk of stomach irritation and ulcers.
Q: Can I take Acenac with Paracetamol for extra pain relief? Paracetamol can generally be combined with Aceclofenac safely — however always confirm with your doctor or pharmacist before combining any medicines.
⚕️ Medical Disclaimer: This information is for general awareness only and does not replace medical advice. Always consult a qualified doctor or pharmacist before taking any prescription medicine.