Drug Class: Antifibrinolytic Agent — Haemostatic | Form: Capsules (Oral) | Prescription Status: Prescription Only (Rx) — DRAP Registered
What is Transamin Capsules 250mg?
Transamin Capsules 250mg contain Tranexamic Acid — an antifibrinolytic medicine (خون کے لوتھڑے کو محفوظ رکھنے والی دوا) used to control or prevent excessive bleeding (ضرورت سے زیادہ خون بہنا). The body naturally forms blood clots (خون کے لوتھڑے) to seal wounds and stop bleeding. Once the wound is healed, the body dissolves these clots through a process called fibrinolysis (خون کے لوتھڑے کا ٹوٹنا). In conditions such as heavy menstrual periods or surgical bleeding, this clot-dissolving process can happen too quickly — leading to prolonged or excessive blood loss. Tranexamic Acid works by blocking the proteins responsible for breaking down clots — allowing them to remain intact for longer and reducing bleeding effectively. Transamin 250mg is a prescription-only medicine and must be used under medical supervision.
What is Transamin 250mg Used For?
Transamin Capsules 250mg is indicated for the control and prevention of the following conditions:
Heavy Menstrual Bleeding — Menorrhagia (حیض میں بہت زیادہ خون آنا) — one of the most common uses of Tranexamic Acid. It significantly reduces the volume of menstrual blood loss without affecting the menstrual cycle or hormonal balance — making it suitable for women who cannot or prefer not to use hormonal treatments
Surgical and Post-Operative Bleeding (آپریشن کے دوران یا بعد میں خون بہنا) — used before and after surgery to reduce blood loss and the need for blood transfusions (خون چڑھانے کی ضرورت کم کرتا ہے) — particularly in dental, orthopaedic, and cardiac surgery
Trauma-Related Bleeding (چوٹ سے خون بہنا) — used in emergency settings to control life-threatening bleeding following serious injury
Nosebleeds — Epistaxis (ناک سے خون بہنا) — used to manage recurrent or difficult-to-control nosebleeds
Bleeding Associated with Clotting Disorders (خون جمنے کی خرابی سے خون بہنا) — used in patients with haemophilia or other bleeding disorders, particularly during or after surgical procedures
Dental Extraction Bleeding (دانت نکلوانے کے بعد خون بہنا) — commonly used to control bleeding following tooth extraction, especially in patients on blood-thinning medicines
How Does Transamin 250mg Work?
Transamin contains Tranexamic Acid — an antifibrinolytic agent that works by competitively blocking plasminogen (پلازمینوجن) — a protein in the blood that, when activated, dissolves blood clots.
Normally, when a blood clot forms to stop bleeding, plasminogen is converted into plasmin — an enzyme that gradually breaks down the clot. In conditions involving excessive bleeding, this process occurs too rapidly or too aggressively — causing clots to dissolve before adequate healing has taken place.
Tranexamic Acid attaches to plasminogen molecules and prevents them from binding to the clot structure — effectively stopping the clot-dissolving process (فبرینولائسس روکتا ہے). This allows the clot to remain stable and intact for longer — reducing blood loss and giving the body sufficient time to complete the natural healing process.
Tranexamic Acid does not create new clots or thicken the blood — it simply prevents existing, medically necessary clots from being broken down too early.
Dosage and Administration
Transamin Capsules must be taken exactly as prescribed by your doctor. Dosage varies depending on the condition being treated (ڈاکٹر کے مشورے کے بغیر خوراک تبدیل نہ کریں).
| Indication | Typical Dose | Duration |
|---|---|---|
| Heavy menstrual bleeding (حیض میں زیادہ خون) | 2 to 3 capsules (500–750mg) three times daily | During menstruation only — up to 4 days |
| Surgical bleeding prevention | As directed by surgeon — typically 1 to 1.5g three times daily | Perioperative period as advised |
| Dental extraction bleeding | 1 to 2 capsules (250–500mg) three to four times daily | 6 to 8 days post-procedure |
| General haemorrhage control | As directed by doctor | As clinically indicated |
Important Administration Instructions:
- Swallow capsules whole with a full glass of water (پانی کے ساتھ پوری کیپسول نگلیں)
- Can be taken with or without food
- For heavy menstrual bleeding — begin treatment on the first day of heavy flow and continue for the duration of heavy bleeding only — do not take throughout the entire menstrual cycle
- Do not exceed the prescribed dose (تجویز کردہ خوراک سے زیادہ نہ لیں)
- If you miss a dose (خوراک بھول جائیں) — take it as soon as you remember. If it is almost time for your next dose, skip the missed one. Never take a double dose.
Active Ingredients
| Ingredient | Role |
|---|---|
| Tranexamic Acid 250mg | Antifibrinolytic agent — blocks plasminogen to prevent premature breakdown of blood clots and reduce excessive bleeding |
Also contains: Sodium bisulfite, sodium lauryl sulfate, and other standard capsule excipients. Please check the product label or ask your pharmacist for full composition details.
Who Should NOT Use Transamin 250mg?
Do not use Transamin if you (استعمال نہ کریں اگر):
- Are allergic to Tranexamic Acid or any other ingredient in the capsule (الرجی ہو)
- Have a history of blood clots (خون کے لوتھڑے) — including deep vein thrombosis (DVT), pulmonary embolism, or stroke (فالج)
- Have a history of convulsions or seizures (مرگی یا دورے)
- Have severe kidney disease (گردے کی شدید بیماری) — Tranexamic Acid is excreted by the kidneys and accumulates in renal impairment
- Are experiencing bleeding in the upper urinary tract (پیشاب کی نالی میں خون آنا) — risk of clot formation in the ureter
Tell your doctor before use if (ڈاکٹر کو بتائیں اگر):
- You have kidney problems (گردے کی بیماری) — dose reduction may be required
- You have a history of thrombosis (خون کا لوتھڑا بننا) or are at increased risk of blood clots
- You are taking hormonal contraceptives (ہارمونل مانع حمل ادویات) — combined use increases the risk of blood clots
- You are pregnant (حاملہ) or breastfeeding (دودھ پلانے والی ماں) — use only if clearly needed and under medical supervision
- You have a colour vision impairment or any eye condition — long-term use of Tranexamic Acid has rarely been associated with visual disturbances
Side Effects
Not everyone will experience side effects. Transamin is generally well tolerated when used at the correct dose for the recommended duration.
Common Side Effects (عام ضمنی اثرات):
- Nausea (متلی) and vomiting (قے) — usually mild — taking with food may help
- Diarrhoea (اسہال) or abdominal discomfort (پیٹ کی تکلیف)
- Dizziness (چکر آنا) — particularly on standing up quickly
- Headache (سردرد)
Serious Side Effects (سنگین ضمنی اثرات — seek immediate medical help):
- Blood clot formation (خون کا لوتھڑا بننا) — signs include sudden leg pain or swelling, chest pain, shortness of breath (سانس لینے میں تکلیف), or sudden severe headache — seek emergency medical help immediately
- Seizures or convulsions (دورے پڑنا) — particularly at high doses — stop the medicine and seek urgent medical attention
- Visual disturbances (نظر میں خرابی) — blurred vision or colour vision changes — stop the medicine and consult an eye specialist promptly
- Allergic reaction (الرجی) — rash, swelling of the face or throat, difficulty breathing — seek emergency help immediately
If any serious side effects occur, stop the medicine and contact your doctor immediately (فوری طور پر ڈاکٹر سے رابطہ کریں).
Drug Interactions
Always inform your doctor and pharmacist about all medicines you are currently taking (تمام ادویات کے بارے میں ڈاکٹر کو بتائیں).
| Medicine / Substance | Effect of Interaction |
|---|---|
| Combined hormonal contraceptives — OCP (مانع حمل گولیاں) | Significantly increases risk of blood clot formation — use with extreme caution and only under medical supervision |
| Factor IX complex concentrates / Anti-inhibitor coagulant concentrates | Increased risk of thrombosis (خون کا لوتھڑا) — avoid combination |
| Tretinoin (all-trans retinoic acid) | May increase risk of thrombotic complications when used together |
| Anticoagulants — e.g. Warfarin (خون پتلا کرنے والی ادویات) | Tranexamic Acid opposes the effect of anticoagulants — combined use requires careful medical monitoring |
| Other haemostatic agents | Additive effect — increased risk of excessive clot formation — use only under medical supervision |
Storage Instructions
- Store below 25°C in a cool, dry place (ٹھنڈی اور خشک جگہ پر رکھیں)
- Keep away from direct sunlight and moisture (دھوپ اور نمی سے دور رکھیں)
- Keep out of reach of children (بچوں کی پہنچ سے دور رکھیں)
- Do not use after the expiry date printed on the pack (میعاد ختم ہونے کے بعد استعمال نہ کریں)
- Store in the original packaging to protect from light and humidity
Frequently Asked Questions (FAQs)
Q: What is Transamin 250mg used for? Transamin 250mg contains Tranexamic Acid — an antifibrinolytic medicine used to control excessive bleeding (ضرورت سے زیادہ خون بہنا). It is most commonly used for heavy menstrual bleeding (حیض میں زیادہ خون آنا), surgical bleeding, dental extraction bleeding, and bleeding associated with clotting disorders. It works by preventing blood clots from breaking down too early — reducing blood loss effectively.
Q: How does Transamin help with heavy menstrual bleeding? During heavy periods, the body's clot-dissolving process can become overactive — breaking down protective clots in the uterus too quickly and allowing continued heavy bleeding. Tranexamic Acid slows this process down — allowing clots to remain intact and reducing menstrual blood loss significantly. Importantly, it does not affect hormonal balance (ہارمونز پر اثر نہیں ڈالتا) or the regularity of the menstrual cycle — making it a suitable option for women who prefer non-hormonal treatment.
Q: Can I take Transamin throughout my entire menstrual cycle? No — Transamin should only be taken during the days of heavy bleeding (بھاری خون بہنے کے دنوں میں) — not throughout the entire cycle. Taking it only when needed reduces the overall dose and the risk of side effects. Your doctor will advise on the exact days and duration most appropriate for your situation.
Q: Is Transamin safe if I am on the contraceptive pill? This combination requires careful medical review. Both Tranexamic Acid and combined hormonal contraceptives (مانع حمل گولیاں) can increase the risk of blood clot formation (خون کا لوتھڑا). Using them together further raises this risk. Always inform your doctor if you are taking any contraceptive before starting Transamin — your doctor will assess whether the combination is appropriate and safe for you.
Q: What are the warning signs of a blood clot I should watch for? Signs of a blood clot (خون کا لوتھڑا) include sudden pain, redness, or swelling in the leg, sudden chest pain, shortness of breath, or sudden severe headache. If you experience any of these symptoms while taking Transamin — stop the medicine immediately and seek emergency medical attention (فوری طور پر ڈاکٹر سے رابطہ کریں).
⚕️ Medical Disclaimer: This product description is for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Transamin is a prescription medicine — always take it exactly as directed by your doctor. Do not use this medicine to self-treat bleeding without proper medical assessment. Consult your doctor immediately if you experience any serious symptoms.
DRAP Registered | Prescription Only (Rx) | For oral use only | Keep out of reach of children