Drug Class: Second-Generation Antihistamine | Form: Oral Tablet | Prescription Status: Available Without Prescription (OTC) — DRAP Registered
What is Rozen 10mg Tablet? Rozen 10mg contains Cetirizine Hydrochloride — a second-generation antihistamine that relieves allergy symptoms by blocking histamine receptors without causing significant sedation seen with older antihistamines. Manufactured by Rasco Pharmaceuticals, it provides effective once-daily relief from allergic rhinitis, urticaria, and other histamine-mediated conditions. Unlike first-generation antihistamines such as Chlorpheniramine, Cetirizine does not readily cross into the brain — making it significantly less sedating and more suitable for daytime use. It is one of the most widely used and well-tolerated antihistamines available for both adults and children above 6 years.
What is Rozen 10mg Used For?
- Allergic rhinitis — seasonal hay fever with runny nose and sneezing (موسمی الرجی — ناک بہنا اور چھینکیں)
- Perennial allergic rhinitis — year-round allergy to dust, pets, and mould (سارا سال رہنے والی الرجی)
- Urticaria — hives and skin wheals causing itching (چھپاکی — جلد پر خارش اور سوجن)
- Allergic conjunctivitis — watery, itchy, red eyes due to allergy (آنکھوں میں خارش اور پانی)
- Angioedema — allergic swelling under the skin (جلد کے نیچے سوجن)
- Allergic skin reactions — itching and rash from environmental triggers (الرجی سے جلد پر خارش)
How Does it Work? Cetirizine selectively blocks peripheral H1 histamine receptors — preventing histamine from binding and triggering allergy symptoms. When the body encounters an allergen, mast cells release histamine which causes the familiar symptoms of sneezing, runny nose, itching, and watery eyes. By occupying H1 receptors before histamine can bind, Cetirizine prevents these symptoms from developing or significantly reduces their intensity. Its selective peripheral action and poor penetration into the brain means it relieves allergy symptoms with minimal sedation compared to older antihistamines.
Dosage and Administration
⚠️ Do not exceed recommended dose. Use with caution in patients with kidney impairment — dose reduction may be required. Avoid alcohol during treatment.
Indication Usual Adult Dose Frequency Notes
Allergic rhinitis / Urticaria
10mg
Once daily
Evening preferred to minimise any drowsiness
Severe allergic symptoms
5mg
Twice daily
As directed by doctor
Children 6 to 12 years
5mg
Twice daily
Half tablet or syrup formulation preferred
Kidney impairment
5mg
Once daily
Dose reduction required — consult doctor
Active Ingredients
Ingredient Strength
Cetirizine Hydrochloride
10mg
Who Should NOT Take Rozen 10mg?
- Allergy to Cetirizine, Hydroxyzine, or any piperazine derivative
- Severe kidney failure requiring dialysis
- Children under 6 years — use paediatric syrup formulation under doctor guidance
- Pregnancy — particularly first trimester; consult doctor before use
- Breastfeeding — Cetirizine passes into breast milk
Side Effects
Common: Mild drowsiness (ہلکی نیند آنا — خاص طور پر شروع میں), dry mouth, mild headache, mild fatigue, mild stomach discomfort — generally well tolerated and usually resolve quickly.
Serious — Seek medical attention immediately: Severe allergic reaction — sudden widespread rash, swelling of face, lips, tongue or throat, difficulty breathing (فوری ہسپتال جائیں), significant urinary retention especially in elderly men with enlarged prostate, severe drowsiness or confusion at standard doses, irregular heartbeat — rare at standard doses but report any palpitations promptly.
Drug Interactions
Medicine Interaction
CNS depressants / sedatives / sleeping tablets
Additive sedation — increased drowsiness even though Cetirizine is low-sedating
Theophylline (high doses)
May slightly reduce Cetirizine clearance — monitor if using high-dose Theophylline
Ritonavir (HIV medicine)
Increases Cetirizine blood levels — increased side effect risk
Anticholinergic medicines
Additive dry mouth and urinary retention risk
Alcohol (شراب)
Increases CNS sedation even with second-generation antihistamines — avoid during treatment
Storage: Store below 25°C in a cool, dry place. Protect from moisture and direct sunlight. Keep out of reach of children (بچوں کی پہنچ سے دور رکھیں). Do not use after expiry date.
FAQs
Q: Can Rozen 10mg be taken every day long-term for chronic allergies? Cetirizine is safe for daily use in chronic allergic conditions like perennial rhinitis and chronic urticaria — however periodic review with your doctor is recommended to assess whether continued use remains necessary.
Q: Will Rozen 10mg make me too drowsy to drive or work? Cetirizine is significantly less sedating than older antihistamines — most patients tolerate it well during the day. However mild drowsiness is possible, especially initially, so observe your personal response before driving or operating machinery.
Q: Can I give Rozen 10mg tablet to my child for allergy symptoms? Rozen 10mg tablet is suitable for children 6 years and above at a reduced 5mg dose — for children under 6 years a paediatric syrup formulation with weight-appropriate dosing under doctor supervision is recommended.
Medical Disclaimer: This information is for general awareness only and does not replace medical advice. Always consult a qualified doctor or pharmacist before giving any medicine to children or if you have an underlying health condition.