Drug Class: Oxazolidinone Antibiotic | Form: Oral Suspension (Syrup) | Prescription Status: Prescription-Only (Rx) — DRAP Registered
What is Nezkil Syrup 100mg/5ml?
Nezkil Syrup 100mg/5ml is a prescription antibiotic suspension containing Linezolid 100mg per 5ml, used to treat serious bacterial infections (بیکٹیریل انفیکشن) in adults and children caused by gram-positive bacteria, including drug-resistant strains. Linezolid belongs to the oxazolidinone class of antibiotics and is particularly effective against infections that do not respond to standard antibiotics, including MRSA (Methicillin-resistant Staphylococcus aureus). The syrup formulation makes it suitable for children and patients who cannot take tablets. It should only be used for confirmed or strongly suspected bacterial infections under close medical supervision.
What is Nezkil Syrup Used For?
Respiratory Tract Infections: Treats pneumonia including hospital-acquired and community-acquired pneumonia caused by susceptible gram-positive bacteria. Skin and Soft Tissue Infections: Treats complicated skin infections including those caused by MRSA that do not respond to standard antibiotics. Bloodstream Infections: Manages septicaemia caused by specific gram-positive bacteria. Bone and Joint Infections: Treats osteomyelitis and joint infections caused by susceptible organisms. Urinary Tract Infections: Used for UTIs caused by gram-positive bacteria when other antibiotics are not suitable.
How Does Nezkil Syrup Work?
Linezolid inhibits bacterial protein synthesis by binding to the 23S ribosomal RNA of the 50S ribosomal subunit, blocking an early step in the bacterial protein-making process. This mechanism is unique to the oxazolidinone class, meaning Linezolid can work against bacteria that have developed resistance to other antibiotic classes including MRSA and vancomycin-resistant strains. By stopping bacteria from producing the proteins they need to survive and multiply, Linezolid brings the infection under control.
Dosage and Administration
| Situation | Dose | Frequency |
|---|---|---|
| Adults and children above 12 years | 600mg (30ml) | Every 12 hours |
| Children below 12 years | Based on body weight as directed by doctor | Every 8 hours |
| As prescribed | Follow doctor's instructions | Complete the full course |
Shake the bottle well before each use. Measure the dose accurately with the measuring spoon or cup provided. Can be taken with or without food. Always complete the full prescribed course even if symptoms improve early.
Active Ingredient
| Ingredient | Role |
|---|---|
| Linezolid 100mg per 5ml | Oxazolidinone antibiotic — inhibits bacterial protein synthesis to treat gram-positive and resistant bacterial infections |
Who Should NOT Use Nezkil Syrup?
Do not use if you have a known allergy to Linezolid. Tell your doctor if you are taking antidepressants, particularly MAO inhibitors or SSRIs, as serious interactions can occur. Inform your doctor if you have high blood pressure, phenylketonuria (this syrup may contain phenylalanine from aspartame), or a history of blood disorders. Tell your doctor if you are pregnant or breastfeeding.
Side Effects
Common: Nausea, diarrhea, headache, insomnia, dizziness, vomiting. Serious (seek immediate help): Signs of low blood cell counts including unusual bruising, bleeding, or persistent fever. Signs of serotonin syndrome including agitation, confusion, rapid heartbeat, and muscle twitching. Optic nerve problems including blurred vision or visual changes with prolonged use.
Storage
Store below 25°C in a dry place away from direct sunlight. Refrigeration is not required. Keep out of reach of children (بچوں کی پہنچ سے دور رکھیں). Do not use after the expiry date. Discard any unused suspension after the period stated on the label once opened.
Frequently Asked Questions
Is Nezkil Syrup safe for children?
Yes. Nezkil Syrup is formulated as a suspension specifically suitable for children. The dose is calculated based on the child's body weight and age and must be determined by a doctor. Never give more than the prescribed amount or use it without a confirmed prescription.
Can I take Nezkil Syrup with my antidepressant medicine?
Linezolid has serious interactions with several antidepressants including MAO inhibitors and SSRIs, which can cause a dangerous condition called serotonin syndrome. Always inform your doctor about every medicine you are taking before starting Nezkil Syrup.
Medical Disclaimer: This description is for informational purposes only and does not replace professional medical advice. Always follow your doctor's prescription and consult your pharmacist for personal guidance.
DRAP Registered | Prescription Required (Rx) | Antibiotic | Gram-Positive and Resistant Bacterial Infections