Drug Class: Beta-1 Selective Adrenergic Blocker | Form: Tablet | Prescription Status: Prescription-Only (Rx) — DRAP Registered
What is Nebivolol 10mg?
Nebivolol 10mg is a prescription beta-blocker tablet containing Nebivolol Hydrochloride equivalent to 10mg Nebivolol base, used to treat high blood pressure (ہائی بلڈ پریشر) and stable chronic heart failure. It is the highest available strength in the Nebivolol range and is used for patients who require stronger blood pressure control beyond what the 5mg dose provides. Nebivolol selectively blocks beta-1 adrenergic receptors in the heart to slow the heart rate and reduce cardiac workload, while also promoting vasodilation through nitric oxide release in blood vessel walls. This dual action makes it effective and well tolerated for long-term cardiovascular management.
What is Nebivolol 10mg Used For?
Hypertension: Treats high blood pressure in adults requiring a higher dose, either alone or alongside other antihypertensive medicines, to reduce the risk of stroke and heart attack. Stable Chronic Heart Failure: Used as part of a combined heart failure treatment plan in patients with mild to moderate stable heart failure, particularly those aged 70 years and above whose dose has been titrated upward from a lower starting strength.
How Does Nebivolol 10mg Work?
Nebivolol selectively blocks beta-1 adrenergic receptors in the heart, reducing the stimulatory effect of adrenaline on the heart muscle. This slows the heart rate and reduces the force of each heartbeat, lowering the workload on the heart and reducing blood pressure. Nebivolol also stimulates the release of nitric oxide from the inner lining of blood vessel walls, causing them to relax and widen. This vasodilation provides an additional blood pressure lowering effect that distinguishes Nebivolol from older, less selective beta-blockers.
Dosage and Administration
| Situation | Dose | Frequency |
|---|---|---|
| Hypertension requiring higher control | 1 tablet (10mg) | Once daily |
| Heart failure titrated dose | As directed by doctor | Once daily |
| As prescribed | Follow doctor's instructions | Do not stop without medical advice |
Take with or without food at the same time each day. Never stop this medicine suddenly. Your doctor will adjust the dose based on your blood pressure response and tolerability.
Active Ingredient
| Ingredient | Role |
|---|---|
| Nebivolol Hydrochloride 10mg | Beta-1 selective blocker — slows heart rate, reduces cardiac workload, and promotes vasodilation to lower blood pressure |
Allergen Warning: These tablets contain lactose monohydrate. Patients with lactose intolerance or galactose intolerance should inform their doctor before use.
Who Should NOT Use Nebivolol 10mg?
Do not use if you have severe heart failure, heart block, very slow heart rate, severe liver disease, severe asthma, or a known allergy to Nebivolol. Tell your doctor if you have diabetes, kidney problems, thyroid disease, or peripheral vascular disease. Inform your doctor if you are pregnant or breastfeeding.
Side Effects
Common: Headache, dizziness, fatigue, slow heart rate, cold hands and feet, nausea. Serious (seek immediate help): Severely slow heart rate or irregular heartbeat, significant worsening of breathlessness or heart failure symptoms, severe allergic reaction including skin rash or facial swelling.
Storage
Store below 25°C in a dry place away from direct sunlight and moisture. Keep out of reach of children (بچوں کی پہنچ سے دور رکھیں). Do not use after the expiry date. Store in original packaging.
Frequently Asked Questions
How is Nebivolol 10mg different from Nebivolol 5mg?
Nebivolol 10mg is prescribed when the standard 5mg dose does not provide adequate blood pressure control. It is not a starting dose and is typically reached after the doctor has confirmed that the lower strength is well tolerated. Both strengths work through the same mechanism but the 10mg provides a stronger and more sustained effect.
Can I stop Nebivolol 10mg suddenly if my blood pressure normalises?
No. Stopping a beta-blocker suddenly can trigger a rebound rise in blood pressure, worsening of angina, or deterioration of heart failure. Always consult your doctor before making any changes to this medicine. If treatment needs to be stopped, your doctor will guide you through a gradual and safe dose reduction.
Medical Disclaimer: This description is for informational purposes only and does not replace professional medical advice. Always follow your doctor's prescription and consult your pharmacist for personal guidance.
DRAP Registered | Prescription Required (Rx) | Hypertension and Heart Failure | Beta-Blocker