Fablous Calcium-C – Advanced Bone Support Supplement

Category: Bone Health, Osteoporosis Prevention & Joint Support Dietary Supplement | Form: Oral Tablet | Pack Size: 30 Tablets | Status: Dietary Supplement — DRAP Registered

What is Fablous Advanced Bone Support Calcium-C?

Fablous Advanced Bone Support Calcium-C is a scientifically formulated bone health supplement combining four complementary bone-building nutrients — Calcium Carbonate 700mg, Vitamin D3 200 IU, Vitamin K2 5mcg, and Magnesium Sulphate 2mg — in a single daily tablet designed to work synergistically to support bone density, reduce the risk of osteoporosis, improve joint health, and support bone mineralisation throughout adult life and particularly during the accelerated bone loss of menopause. What distinguishes this formulation from basic calcium supplements is the inclusion of all four nutrients that work together in the bone mineralisation pathway — Calcium provides the structural mineral substrate for bone matrix, Vitamin D3 ensures calcium is absorbed from the gut and directed toward bone, Vitamin K2 activates the proteins that anchor calcium within bone tissue rather than allowing it to deposit in arteries, and Magnesium regulates the enzymes responsible for bone matrix protein synthesis and Vitamin D3 activation. Without all four of these nutrients present together, supplemental calcium alone is poorly utilised — absorbed into the bloodstream but not efficiently incorporated into bone mineral matrix and potentially depositing in vascular walls. Fablous Advanced Bone Support Calcium-C addresses this limitation by delivering the complete four-nutrient system for optimal calcium utilisation and bone health — making it particularly valuable for postmenopausal women (جوڑوں اور ہڈیوں کی صحت), the elderly, and anyone at increased risk of bone density loss.

What is Fablous Advanced Bone Support Calcium-C Used For?

• Osteoporosis prevention and support — providing the essential mineral and vitamin nutrients for maintaining bone mineral density and reducing the risk of fractures in at-risk adults (ہڈیوں کی کمزوری)
• Menopausal bone loss — nutritional support for the accelerated bone mineral density decline that occurs during and after menopause as oestrogen levels fall (حیض کی بندش کے بعد ہڈیوں کا تحفظ)
• Joint pain support — calcium and magnesium contributing to healthy cartilage and joint tissue function — reducing joint discomfort associated with bone density loss and ageing (جوڑوں کا درد)
• Bone mineralisation — providing the nutritional foundation for ongoing bone matrix mineralisation throughout adult life
• Calcium deficiency — supplementing inadequate dietary calcium intake from dairy, green vegetables, and other food sources (کیلشیم کی کمی)
• Vitamin D deficiency — correcting Vitamin D insufficiency — extremely common in Pakistan — that impairs calcium absorption and bone mineralisation (وٹامن ڈی کی کمی)
• Fracture risk reduction — supporting bone strength and density to reduce the risk of fragility fractures particularly in the hip, spine, and wrist in older adults
• Post-fracture bone recovery — nutritional support for bone healing and remineralisation following fractures under medical supervision
• Elderly bone health — supporting bone mineral density maintenance in older adults where both calcium absorption and Vitamin D synthesis decline with age

How Does Fablous Advanced Bone Support Calcium-C Work?

The four ingredients in Fablous Advanced Bone Support Calcium-C work as an integrated nutritional system — each addressing a specific and essential step in the bone mineralisation process:

Calcium Carbonate 700mg — Primary Bone Mineral Substrate:

Calcium is the most abundant mineral in the human body — approximately 99% of total body calcium is stored in bones and teeth as hydroxyapatite crystals (Ca10(PO4)6(OH)2) — the mineral phase that gives bone its compressive strength and structural rigidity. The remaining 1% of body calcium circulates in the blood and intracellular compartments where it serves critical physiological functions including muscle contraction, nerve impulse transmission, cardiac rhythm, blood clotting, and hormone secretion. The body maintains blood calcium within a very narrow range — when dietary calcium intake is insufficient, parathyroid hormone (PTH) stimulates the release of calcium from bone mineral stores to maintain blood levels — progressively depleting bone mineral density over time. Calcium Carbonate is the most concentrated form of supplemental calcium — containing 40% elemental calcium by weight — meaning 700mg of Calcium Carbonate provides 280mg of elemental calcium per tablet. This elemental calcium replenishes dietary shortfalls — reducing the PTH-driven withdrawal of calcium from bone and providing substrate for ongoing bone mineralisation. Calcium Carbonate is best absorbed when taken with food — stomach acid produced during meals converts Calcium Carbonate to soluble calcium chloride for optimal intestinal absorption.

Vitamin D3 200 IU — Calcium Absorption and Bone Mineralisation Regulator:

Vitamin D3 (cholecalciferol) is the master regulator of calcium homeostasis in the body — without adequate Vitamin D3, even generous dietary calcium intake cannot be effectively absorbed from the intestine. After ingestion, Vitamin D3 is hydroxylated in the liver to 25-hydroxyvitamin D (calcidiol) and then in the kidneys to the fully active form 1,25-dihydroxyvitamin D (calcitriol). Calcitriol acts on intestinal epithelial cells to upregulate the expression of calcium transport proteins — TRPV6 channels and calbindin D9k — that actively pump dietary calcium across the intestinal wall into the bloodstream, increasing calcium absorption efficiency from approximately 10 to 15% without Vitamin D3 to 30 to 40% with adequate Vitamin D3. Calcitriol also acts directly on osteoblasts — bone-forming cells — to promote bone matrix protein synthesis and mineralisation, and on the kidneys to reduce calcium excretion in urine — maximising the retention and utilisation of absorbed dietary and supplemental calcium. Pakistan has among the highest global rates of Vitamin D deficiency due to indoor lifestyles, air pollution reducing UV penetration, and cultural dress practices limiting skin sun exposure — making Vitamin D3 supplementation an important nutritional intervention for the majority of the Pakistani population regardless of age.

Vitamin K2 (Menaquinone) 5mcg — Calcium Directing and Vascular Protection:

Vitamin K2 is one of the most critically underappreciated nutrients in bone health — it does not build bone directly but serves as the essential cofactor for activating two key proteins that determine where calcium is deposited in the body. The first is Osteocalcin — a protein produced by osteoblasts that, when activated (carboxylated) by Vitamin K2, binds calcium ions within the bone matrix and anchors them into the hydroxyapatite crystal lattice. Without adequate Vitamin K2, Osteocalcin remains undercarboxylated and inactive — calcium cannot be effectively incorporated into bone even when it is present in the bloodstream in adequate amounts. The second is Matrix Gla Protein (MGP) — produced by vascular smooth muscle cells and cartilage cells, which when activated by Vitamin K2, inhibits vascular calcification by preventing calcium from depositing in arterial walls. This dual action of Vitamin K2 — simultaneously directing calcium into bone where it belongs and preventing it from depositing in arteries where it causes cardiovascular harm — resolves the longstanding concern that calcium supplementation without Vitamin K2 may increase cardiovascular risk by promoting arterial calcification. At 5mcg, Fablous provides a meaningful contribution to daily Vitamin K2 requirements — supporting the optimal routing of calcium to bone while maintaining vascular health.

Magnesium Sulphate 2mg — Bone Matrix Enzyme Cofactor and Vitamin D3 Activator:

Magnesium is the fourth most abundant mineral in the human body and a cofactor for over 300 enzymatic reactions — including several that are directly essential for bone health. In bone mineralisation, magnesium is a structural component of hydroxyapatite crystals — influencing crystal size, shape, and stability — and a cofactor for alkaline phosphatase, the primary enzyme responsible for initiating mineralisation of the organic bone matrix (osteoid). Magnesium is also essential for the enzymatic activation of Vitamin D3 — both the hepatic 25-hydroxylation and the renal 1-alpha-hydroxylation steps that convert inactive Vitamin D3 to its active calcitriol form require magnesium-dependent enzymes. Magnesium deficiency impairs Vitamin D3 activation — meaning that correcting Vitamin D3 deficiency through supplementation is less effective without adequate magnesium status. Additionally, magnesium regulates PTH secretion — low magnesium paradoxically impairs PTH secretion while also causing PTH resistance in target tissues, disrupting the hormonal regulation of calcium and phosphate balance. Magnesium also contributes to muscle function — including the muscles surrounding joints — supporting joint stability and reducing the muscle cramping that often accompanies bone density loss in postmenopausal women.

Dosage and Administration

⚠️ Always take as directed or as advised by your doctor. Take with food for optimal Calcium Carbonate absorption. Never exceed the recommended dose without medical guidance. Assess total daily calcium intake from all dietary and supplemental sources.

Usage Guidelines:

• Take with food — Calcium Carbonate requires stomach acid produced during meals for optimal dissolution and absorption; taking on an empty stomach significantly reduces calcium absorption
• For maximum absorption, if taking 2 tablets daily — split doses between morning and evening meals rather than taking both at once; the intestine has a limited calcium absorption capacity per dose and splitting doses maximises total daily absorption
• Assess total daily calcium intake from all sources — dietary calcium from dairy products, green leafy vegetables, fortified foods, and other supplements should be considered alongside Fablous Calcium-C; total daily calcium intake should generally not exceed 2000mg from all sources in adults
• Consistent daily supplementation is essential — bone mineralisation is a continuous ongoing process; irregular supplementation provides inconsistent nutritional support
• For postmenopausal women — supplementation should be part of a comprehensive bone health strategy including weight-bearing exercise, adequate protein intake, fall prevention measures, and regular bone density monitoring (DEXA scan) under medical supervision
• Vitamin D3 at 200 IU per tablet is a relatively modest dose — your doctor may recommend additional Vitamin D3 supplementation based on your measured 25-hydroxyvitamin D blood levels, which ideally should be maintained above 50 nmol/L for optimal calcium absorption and bone health

Active Ingredients Per Tablet

 

Who Should NOT Take Fablous Advanced Bone Support Calcium-C?

Do not take if you:

• Have hypercalcaemia (elevated blood calcium) — additional calcium supplementation is contraindicated; symptoms include excessive thirst, frequent urination, confusion, and muscle weakness
• Have hypercalciuria (excessive calcium in urine) — increases kidney stone risk significantly with calcium supplementation
• Have a history of calcium-containing kidney stones — particularly calcium oxalate stones; discuss with your urologist or nephrologist before starting
• Have sarcoidosis, hyperparathyroidism, or other conditions causing Vitamin D hypersensitivity — Vitamin D3 raises calcium absorption and risks dangerous hypercalcaemia
• Have severe kidney disease (eGFR below 30 mL/min) — impaired renal calcium and Vitamin D metabolism; calcium and Vitamin D supplementation requires specialist nephrology guidance
• Are taking Digoxin — hypercalcaemia from calcium and Vitamin D significantly increases Digoxin toxicity risk

Always consult your doctor before taking Fablous Calcium-C if you:

• Have mild to moderate kidney disease (گردے کی بیماری) — monitor blood and urine calcium regularly
• Have a history of kidney stones of any type (گردے کی پتھری) — calcium supplementation may increase stone risk in susceptible individuals
• Have cardiovascular disease — discuss appropriate calcium supplementation with your cardiologist; Vitamin K2 supports vascular calcium management
• Are taking Warfarin or other Vitamin K antagonist anticoagulants — Vitamin K2, even at 5mcg, may interact with Warfarin's anticoagulant mechanism; monitor INR and inform your haematologist
• Are taking thyroid medicine (Levothyroxine) — calcium significantly reduces Levothyroxine absorption; take at least 4 hours apart
• Are taking bisphosphonates (e.g., Alendronate) for osteoporosis — calcium reduces bisphosphonate absorption; take at least 2 hours apart
• Are taking iron supplements — calcium reduces iron absorption; take at least 2 hours apart
• Are taking fluoroquinolone or tetracycline antibiotics — calcium reduces their absorption; take at least 2 hours apart
• Are pregnant or breastfeeding — calcium and Vitamin D supplementation during pregnancy and breastfeeding is generally safe and often recommended; confirm appropriate doses with your obstetrician
• Are taking thiazide diuretics — reduce renal calcium excretion; combined with calcium supplementation increases hypercalcaemia risk

Side Effects

Common and Generally Mild:

• Constipation — most common calcium supplement side effect; increase fluid and dietary fibre intake; splitting the daily dose may help
• Mild bloating or flatulence — from Calcium Carbonate reacting with stomach acid; taking with food minimises this
• Mild nausea or stomach discomfort — taking with food significantly reduces this
• Chalky or unpleasant taste — Calcium Carbonate related; drink a full glass of water with each tablet

Monitor and Report to Your Doctor:

• Symptoms of hypercalcaemia — excessive thirst, frequent urination, nausea, constipation, muscle weakness, confusion, or kidney pain — from excess total daily calcium intake across all sources; seek immediate medical evaluation
• New or worsening kidney stone symptoms — severe flank or back pain, blood in urine, painful urination — stop supplementation and seek urgent urological evaluation
• Changes in anticoagulation control — if taking Warfarin; even small amounts of Vitamin K2 can affect INR stability; monitor INR more frequently when starting or stopping supplementation
• Worsening constipation that does not respond to dietary measures — reduce dose or discuss with your doctor

Drug Interactions

 

Storage Instructions

• Store below 25°C in a cool, dry place
• Protect from moisture and direct sunlight — Calcium Carbonate is hygroscopic and absorbs moisture from the air
• Keep in original blister pack until use
• Keep out of reach of children (بچوں کی پہنچ سے دور رکھیں)
• Do not use after the expiry date printed on the pack

Frequently Asked Questions (FAQs)

Q: Why does Fablous Calcium-C include Vitamin K2 alongside calcium and Vitamin D3?

Vitamin K2 activates Osteocalcin — the protein that anchors calcium into bone mineral matrix — and Matrix Gla Protein which prevents calcium from depositing in arteries; without Vitamin K2, supplemental calcium absorbed through Vitamin D3 may not be efficiently incorporated into bone and may increase arterial calcification risk; Vitamin K2 ensures calcium goes to bone where it is needed.

Q: Why must Fablous Calcium-C be taken with food?

Calcium Carbonate requires stomach acid produced during meals to dissolve into absorbable calcium ions — taking on an empty stomach when acid secretion is minimal reduces calcium absorption by up to 50%; always take with a main meal for maximum absorption efficiency.

Q: Can Fablous Calcium-C be taken alongside my osteoporosis medicine (bisphosphonate)?

Yes — but timing is critical; bisphosphonates like Alendronate must be taken on an empty stomach and Fablous Calcium-C must be taken with food; ensure at least 2 hours of separation between bisphosphonate dosing and Fablous Calcium-C to prevent the calcium from blocking bisphosphonate absorption.

Q: Is the Vitamin D3 dose of 200 IU per tablet sufficient for bone health?

200 IU per tablet contributes to daily Vitamin D3 intake — however many adults, particularly in Pakistan where Vitamin D deficiency is extremely prevalent, require 1000 to 2000 IU or more daily to achieve optimal blood levels; ask your doctor to measure your 25-hydroxyvitamin D blood level and advise whether additional Vitamin D3 supplementation is needed alongside Fablous Calcium-C.

Medical Disclaimer: Fablous Advanced Bone Support Calcium-C is a dietary supplement — not a pharmaceutical medicine. It is not intended to diagnose, treat, cure, or prevent any disease including osteoporosis. Osteoporosis is a serious medical condition requiring diagnosis by DEXA scan and management under a qualified physician's supervision — nutritional supplementation supports but does not replace medical evaluation and treatment. Always assess total daily calcium intake from all dietary and supplemental sources.