Drug Class: Proton Pump Inhibitor + Antacid Combination | Form: Oral Capsule | Manufacturer: CCL Pharmaceuticals | Prescription Status: Prescription Only (Rx) — DRAP Registered
What is Faast Plus 40mg Capsule?
Faast Plus 40mg is a unique dual-action anti-ulcer capsule manufactured by CCL Pharmaceuticals — combining Omeprazole 40mg, a proven proton pump inhibitor (PPI) that reduces stomach acid production at its source, with Sodium Bicarbonate 1100mg, a fast-acting antacid that immediately neutralises existing stomach acid. This combination solves one of the key limitations of standard Omeprazole — the need to take it 30 to 60 minutes before meals for adequate absorption. Sodium Bicarbonate raises the gastric pH immediately — protecting Omeprazole from acid degradation in the stomach and allowing it to be absorbed rapidly and effectively regardless of meal timing. The result is faster onset of acid suppression, stronger overall acid control, and immediate symptomatic relief — making Faast Plus 40mg suitable for conditions requiring rapid and sustained reduction of stomach acid including peptic ulcers, acid reflux (سینے کی جلن), and NSAID-induced gastric damage.
What is Faast Plus 40mg Used For?
- Gastroesophageal reflux disease (GERD) — treatment of acid reflux causing persistent heartburn and acid regurgitation (معدے کا تیزاب اوپر آنا)
- Peptic ulcer disease — treatment of stomach and duodenal ulcers including those caused by H. pylori or long-term NSAID use (معدے کا السر)
- Erosive oesophagitis — healing of acid-induced erosions and inflammation in the oesophageal lining (غذائی نالی کی سوزش)
- H. pylori eradication — used alongside antibiotics to eliminate H. pylori infection causing recurrent peptic ulcers
- NSAID-induced ulcer prevention — protecting the stomach lining in patients requiring long-term NSAID or Aspirin therapy
- Zollinger-Ellison syndrome — management of excessive acid production from gastrin-secreting tumours
- Immediate acid relief — the Sodium Bicarbonate component provides rapid neutralisation of excess stomach acid while Omeprazole's suppressive effect builds up
How Does Faast Plus 40mg Work?
Omeprazole 40mg — Proton Pump Inhibitor: The stomach produces acid through specialised parietal cells — inside which a protein called hydrogen-potassium ATPase (the proton pump) actively transports hydrogen ions into the stomach, creating the highly acidic gastric environment. Omeprazole is absorbed from the small intestine into the bloodstream, concentrated in the acid-secreting parietal cells, and converted into its active sulphenamide form — irreversibly binding to and blocking the proton pump. This stops hydrogen ion secretion at the final and most critical step of acid production — reducing gastric acid output by up to 90% throughout the day. Because Omeprazole irreversibly inactivates each proton pump it binds to, acid suppression lasts for 24 hours from a single dose — with full therapeutic effect building progressively over the first 3 to 5 days as more pumps are blocked.
Sodium Bicarbonate 1100mg — Antacid and Omeprazole Protector: Sodium Bicarbonate serves two important clinical roles in Faast Plus. First, it acts as an immediate antacid — rapidly neutralising existing stomach acid within minutes of ingestion and providing fast symptomatic relief from heartburn and acid discomfort. Second and critically — it raises gastric pH transiently — creating an alkaline microenvironment around the Omeprazole molecules as they dissolve in the stomach. Standard Omeprazole capsules require enteric coating to protect the drug from stomach acid degradation before intestinal absorption. The Sodium Bicarbonate in Faast Plus replaces this requirement — protecting uncoated Omeprazole from acid degradation and ensuring rapid and consistent absorption even when taken without regard to meal timing.
Combined Dual Effect: Sodium Bicarbonate provides immediate acid neutralisation for fast symptom relief while Omeprazole delivers sustained, powerful acid suppression lasting 24 hours — together providing both rapid onset and prolonged duration of acid control that neither component achieves as effectively alone.
Dosage and Administration
⚠️ Always take exactly as prescribed by your doctor. Never exceed the prescribed dose. Do not take more than one Faast Plus 40mg capsule per day unless specifically directed by your doctor.
| Indication | Usual Adult Dose | Frequency | Duration |
|---|---|---|---|
| GERD — symptom relief | 1 capsule (40mg) | Once daily | 4 weeks |
| Erosive oesophagitis — healing | 1 capsule (40mg) | Once daily | 4–8 weeks |
| Peptic ulcer — treatment | 1 capsule (40mg) | Once daily | 4–8 weeks |
| H. pylori eradication | 1 capsule (40mg) | Once or twice daily | 7–14 days with antibiotics |
| NSAID-induced ulcer prevention | 1 capsule (40mg) | Once daily | Duration of NSAID therapy |
| Zollinger-Ellison syndrome | As prescribed | Under specialist supervision | Long-term |
Critical Dosing Rules:
- Unlike standard Omeprazole, Faast Plus can be taken without strict 30–60 minute pre-meal timing — the Sodium Bicarbonate protects Omeprazole absorption regardless of meal timing; however consistent daily timing is still recommended
- The high Sodium Bicarbonate content (1100mg per capsule) contributes significant sodium load — patients on sodium-restricted diets, those with heart failure, hypertension, or kidney disease must inform their doctor before use
- Do not use Faast Plus for longer than prescribed without medical review — long-term PPI use carries risks including magnesium deficiency, bone density reduction, and increased susceptibility to gut infections
- For H. pylori eradication, Faast Plus must always be taken alongside prescribed antibiotics — never use alone for H. pylori
- If symptoms do not improve after 4 weeks, consult your doctor — persistent symptoms require investigation for an underlying cause
How to Take:
- Swallow the capsule whole with a full glass of water
- May be taken with or without food — unlike standard Omeprazole, meal timing is flexible with Faast Plus
- Take at the same time each day for consistent acid suppression
- If a dose is missed, take it as soon as remembered — skip if it is nearly time for the next dose; never double the dose
Active Ingredients
| Ingredient | Strength per Capsule |
|---|---|
| Omeprazole | 40mg |
| Sodium Bicarbonate | 1100mg |
Who Should NOT Take Faast Plus 40mg?
Do not take if you:
- Are allergic to Omeprazole, any other PPI (e.g., Esomeprazole, Pantoprazole), or any ingredient in the capsule
- Are on a strict sodium-restricted diet — each capsule contains 1100mg Sodium Bicarbonate contributing significant sodium
- Have severe metabolic alkalosis — Sodium Bicarbonate can worsen alkalotic states
- Are taking Nelfinavir (HIV medicine) — PPIs significantly reduce its absorption
- Are under 18 years of age unless specifically prescribed
Always consult your doctor before taking Faast Plus if you have:
- Heart failure or hypertension (ہائی بلڈ پریشر) — high sodium content from Sodium Bicarbonate may worsen fluid retention and raise blood pressure
- Kidney disease (گردے کی بیماری) — Sodium Bicarbonate is renally cleared; accumulation risk in impaired kidneys
- Severe liver disease (جگر کی بیماری) — Omeprazole metabolism significantly reduced; dose adjustment may be required
- Osteoporosis or low bone density — long-term PPI use reduces calcium absorption
- Low magnesium levels — long-term PPI use can cause hypomagnesaemia
- Are pregnant or breastfeeding — use only when clearly necessary under medical supervision
- Are elderly — increased risk of fractures and Clostridium difficile infection with long-term PPI use
- Have unexplained weight loss, difficulty swallowing, persistent vomiting, or blood in stools — urgent investigation required before starting any PPI
Side Effects
Common Side Effects:
- Headache — most commonly reported PPI side effect; usually mild and temporary
- Nausea or stomach discomfort — mild and usually settles with continued use
- Diarrhoea or constipation — altered gut environment from acid suppression
- Flatulence or bloating — mild and usually temporary
- Increased thirst — Sodium Bicarbonate related
- Mild abdominal discomfort — usually resolves within the first week
Serious Side Effects — Stop Taking and Seek Medical Help Immediately:
- Severe allergic reaction — swelling of face, lips, tongue or throat, difficulty breathing, widespread rash or hives (یہ طبی ہنگامی صورتحال ہے)
- Severe skin reactions — Stevens-Johnson syndrome, toxic epidermal necrolysis — widespread blistering or peeling skin; rare but life-threatening; stop immediately
- Metabolic alkalosis — from excess Sodium Bicarbonate accumulation; symptoms include muscle twitching, hand tremors, confusion, nausea — particularly in kidney disease patients
- Clostridium difficile infection — severe watery or bloody diarrhoea, abdominal cramps, fever — long-term acid suppression increases susceptibility
- Hypomagnesaemia (low magnesium) — muscle cramps, tremors, irregular heartbeat, or seizures — with prolonged PPI use; monitor magnesium with long-term treatment
- Severe liver reaction — yellowing of skin or eyes (یرقان), dark urine, extreme fatigue — rare; stop immediately and seek medical attention
- Bone fractures — long-term high-dose PPI use increases hip, wrist, and spine fracture risk through reduced calcium absorption — particularly in elderly patients
- Fluid retention or worsening hypertension — Sodium Bicarbonate sodium load can worsen blood pressure and fluid retention in susceptible patients
Drug Interactions
| Medicine / Substance | Possible Interaction |
|---|---|
| Clopidogrel (antiplatelet) | Omeprazole significantly reduces Clopidogrel conversion to its active form — reducing its cardioprotective antiplatelet effect; use Pantoprazole as the preferred PPI alternative alongside Clopidogrel |
| Nelfinavir (HIV medicine) | Contraindicated — Omeprazole significantly reduces Nelfinavir absorption and antiretroviral effectiveness |
| Atazanavir / other HIV protease inhibitors | PPIs reduce absorption of these antiretroviral medicines — avoid or use under HIV specialist supervision |
| Methotrexate | PPIs reduce Methotrexate clearance — serious toxicity risk at high doses; consider temporary PPI suspension during high-dose Methotrexate cycles |
| Warfarin / anticoagulants | Omeprazole may increase anticoagulant effect — monitor INR closely at initiation and dose changes |
| Ketoconazole / Itraconazole (antifungals) | Raised gastric pH reduces absorption of these antifungals — may reduce antifungal effectiveness |
| Iron supplements | Raised gastric pH reduces iron absorption — take iron at least 2 hours before or after Faast Plus |
| Digoxin | Raised gastric pH increases Digoxin absorption — monitor Digoxin levels and cardiac status carefully |
| Sodium-retaining medicines (e.g., corticosteroids, NSAIDs) | Additive sodium retention from Sodium Bicarbonate — worsening fluid retention and blood pressure; monitor closely |
| Quinidine / other medicines affected by urinary pH | Sodium Bicarbonate raises urinary pH — may alter excretion rates of pH-sensitive medicines; inform your doctor |
| Alcohol (شراب) | Directly irritates the stomach lining and counteracts the acid-healing effect of Omeprazole — avoid completely during treatment |
Storage Instructions
- Store below 25°C in a cool, dry place
- Protect from moisture and direct sunlight
- Keep in original packaging until use
- Keep out of reach of children (بچوں کی پہنچ سے دور رکھیں)
- Do not use after the expiry date printed on the pack
Frequently Asked Questions (FAQs)
Q: Why does Faast Plus not need to be taken before meals like regular Omeprazole? The Sodium Bicarbonate in Faast Plus immediately raises gastric pH — protecting Omeprazole from stomach acid degradation and enabling rapid absorption without requiring the strict pre-meal timing that standard enteric-coated Omeprazole needs.
Q: Is the high Sodium Bicarbonate content in Faast Plus safe for heart or blood pressure patients? Patients with heart failure, hypertension, or kidney disease must consult their doctor before using Faast Plus — the 1100mg Sodium Bicarbonate per capsule contributes a significant sodium load that can worsen fluid retention and raise blood pressure in susceptible patients.
Q: Can Faast Plus 40mg be taken with Clopidogrel for heart protection? No — Omeprazole significantly reduces the effectiveness of Clopidogrel's blood-thinning effect; Pantoprazole-based alternatives are strongly preferred for patients requiring both a PPI and Clopidogrel for cardiac protection.
Q: How long can Faast Plus 40mg be taken continuously? Faast Plus is intended for short to medium-term use under medical supervision — long-term continuous use increases the risk of magnesium deficiency, reduced bone density, and gut infections; always consult your doctor for regular review if ongoing acid suppression is needed.
Medical Disclaimer: This information is for general awareness only and does not replace advice from your doctor or pharmacist. Unexplained or persistent stomach symptoms — including difficulty swallowing, unintentional weight loss, or blood in stools — must always be investigated by a doctor before starting any acid-suppressing medicine. Never self-medicate with PPIs for prolonged periods without medical supervision.
