Eyebradex Eye Drops 5ml (Tobramycin + Dexamethasone)

Drug Class: Topical Ophthalmic Antibiotic + Corticosteroid Combination | Form: Eye Drops (Ophthalmic Suspension) | Prescription Status: Prescription Only (Rx) — DRAP Registered

What is Eyebradex Eye Drops 5ml?

Eyebradex Eye Drops 5ml is a combination eye drop medicine containing two active ingredients — Tobramycin, a powerful aminoglycoside antibiotic, and Dexamethasone, a potent corticosteroid (steroid). It is used to treat inflammatory conditions of the eye (آنکھ کی سوزش) where bacterial infection is present or there is a risk of bacterial infection developing. Tobramycin kills the bacteria causing or threatening infection while Dexamethasone rapidly reduces the swelling, redness, pain, and inflammatory response in the eye. Together they provide comprehensive treatment — addressing both the infection and the inflammation simultaneously in a single preparation. Eyebradex Eye Drops are used for a range of serious eye conditions including severe allergic eye reactions, corneal injuries, and inflammation following eye surgery. They must only be used as prescribed by your doctor and must never be used for longer than the prescribed duration — prolonged steroid eye drops carry serious risks including raised eye pressure and cataract formation.

What is Eyebradex Eye Drops Used For?

Eyebradex Eye Drops 5ml is approved for the treatment of the following conditions:

• Steroid-Responsive Ocular Inflammatory Conditions with Bacterial Infection — eye conditions involving significant inflammation where bacterial infection is also confirmed or strongly suspected (آنکھ کی سوزش جس میں بیکٹیریل انفیکشن بھی ہو)
• Post-Operative Ocular Inflammation — inflammation of the eye following eye surgery — including cataract surgery — where preventing bacterial infection is also important (آپریشن کے بعد آنکھ کی سوزش)
• Corneal Injury with Risk of Infection — superficial injuries to the cornea (آنکھ کی سطح کی چوٹ) where inflammation needs to be controlled and bacterial infection prevented
• Severe Allergic Eye Conditions with Secondary Bacterial Infection — severe eye allergies complicated by bacterial infection requiring both antibiotic and anti-inflammatory treatment
• Anterior Uveitis (Iritis) — inflammation of the front part of the eye involving the iris and surrounding structures where bacterial risk is present
• Blepharokeratoconjunctivitis — combined inflammation of the eyelids, cornea, and conjunctiva with bacterial involvement
• Chronic Anterior Segment Inflammation — long-term inflammation of the front structures of the eye requiring steroid treatment alongside infection prevention

How Does Eyebradex Eye Drops Work?

Eyebradex Eye Drops combine two medicines that target bacterial infection and inflammation through different but highly complementary mechanisms:

Tobramycin (Aminoglycoside Antibiotic): Tobramycin kills bacteria by penetrating bacterial cells and binding irreversibly to their ribosomes — the internal structures that bacteria use to produce the proteins essential for their survival, growth, and reproduction. By disrupting this protein production process, Tobramycin prevents bacteria from functioning normally and causes them to die. This is a bactericidal action — meaning Tobramycin actively kills bacteria rather than just stopping them from multiplying. It is effective against a broad range of bacteria responsible for eye infections — particularly Gram-negative organisms such as Pseudomonas aeruginosa, Escherichia coli, and Haemophilus influenzae, as well as Gram-positive organisms including Staphylococcus aureus and Streptococcus species. When applied as eye drops, Tobramycin reaches high concentrations in the tear film and ocular surface — delivering a powerful local antibacterial effect with minimal absorption into the bloodstream.

Dexamethasone (Corticosteroid — Steroid): When the eye is infected, injured, or exposed to allergens, the body's immune system triggers an inflammatory response — releasing prostaglandins, histamines, and cytokines that cause redness, swelling, pain, light sensitivity, and discharge. While inflammation is a natural defence mechanism, excessive or prolonged ocular inflammation can damage delicate eye structures, impair vision, and delay healing. Dexamethasone is one of the most potent topical corticosteroids available for ophthalmic use. It suppresses the inflammatory response by blocking the production and release of these inflammatory chemicals — rapidly reducing redness, swelling, pain, and light sensitivity in the eye. By controlling inflammation, Dexamethasone also helps protect delicate eye structures from inflammatory damage and creates a better healing environment within the eye. The combination with Tobramycin ensures that while inflammation is being suppressed, any bacterial infection is simultaneously being eliminated — preventing the risk of a worsening infection that might otherwise be masked by the steroid's anti-inflammatory effect.

Dosage and Administration

⚠️ For use in the eye only — never use in the ear. Never swallow eye drops. Always wash hands before applying. Do not allow the dropper tip to touch the eye, eyelids, or any surface — this prevents contamination. Always follow your doctor's prescribed dose and duration exactly. Never use for longer than prescribed — prolonged steroid eye drops can cause serious and permanent eye damage.

How to Apply Eyebradex Eye Drops Correctly:

1. Wash your hands thoroughly with soap and water before handling the bottle
2. Shake the bottle gently before each use — this is an ophthalmic suspension and must be shaken to mix the medicine evenly
3. Remove the cap carefully
4. Tilt your head backward and look upward toward the ceiling
5. Gently pull the lower eyelid downward with a clean finger to create a small pocket between the eyelid and the eye
6. Hold the bottle upside down just above the eye — do not let the dropper tip touch the eye, eyelashes, or any surface
7. Squeeze the bottle gently to release exactly 1 drop into the lower eyelid pocket — do not blink immediately
8. Close the eye gently and press the inner corner of the eye (near the nose) with a clean finger for 1 to 2 minutes — this is called nasolacrimal occlusion and prevents the drops from draining into the throat and reduces systemic absorption
9. Gently wipe away any excess drops from around the eye with a clean tissue
10. If a second drop is prescribed, wait at least 5 minutes before applying it
11. If using other eye drops at the same time, always wait at least 5 minutes between different preparations
12. Replace the cap tightly after every use

• Complete the full prescribed course even if the eye feels better — stopping early risks infection or inflammation returning
• Do not wear contact lenses during treatment — consult your doctor before resuming lens wear after completing the course
• Treatment duration is usually 7 to 14 days depending on the condition — never extend without doctor review
• Your doctor may monitor your eye pressure (intraocular pressure) during treatment with steroid eye drops

Active Ingredients

Who Should NOT Use Eyebradex Eye Drops?

Do not use these drops if you:

• Are allergic to Tobramycin, Dexamethasone, any other aminoglycoside antibiotic (e.g., Gentamicin, Neomycin), or any corticosteroid medicine
• Have a viral eye infection — including Herpes simplex keratitis (dendritic ulcer), vaccinia, or varicella infection of the eye. Dexamethasone steroid can cause viral infections to spread rapidly and cause serious, potentially permanent eye damage
• Have a fungal eye infection — steroids worsen fungal infections — antifungal treatment is required instead
• Have acute purulent (pus-forming) untreated bacterial eye infection — a proper diagnosis must be established before steroid-containing drops are used
• Have mycobacterial eye infections — including tuberculosis of the eye
• Have glaucoma or a known history of steroid-induced raised eye pressure (انٹراوکولر پریشر میں اضافہ) — Dexamethasone can raise eye pressure and worsen glaucoma
• Have a known corneal ulcer — steroids can worsen corneal ulceration and delay healing
• Are wearing soft contact lenses during treatment — contact lenses must be removed before applying drops
• Are under 2 years of age — safety in very young children has not been fully established — consult a specialist

Tell your doctor before use if you have:

• A personal or family history of glaucoma — steroid eye drops can raise intraocular pressure
• A history of herpes simplex infection of the eye — even inactive — steroid drops can reactivate the virus
• Diabetes — diabetic patients are more susceptible to steroid-induced raised eye pressure and cataract formation
• A history of cataract — prolonged steroid eye drop use can accelerate cataract formation
• Had recent eye surgery — confirm with your eye surgeon before using any steroid-containing drops
• If you are pregnant or breastfeeding — your doctor will carefully assess safety before prescribing

Side Effects

Like all medicines, Eyebradex Eye Drops can cause side effects. Not everyone will experience them. Most side effects are related to the Dexamethasone steroid component and are more likely with prolonged use.

Common Side Effects (relatively frequent):

• Mild temporary stinging, burning, or discomfort immediately after applying the drops — usually settles within a few minutes
• Mild temporary blurring of vision immediately after application — wait for vision to clear before driving or operating machinery
• Eye redness or irritation — usually mild and temporary
• Watery eyes or increased tear production — temporary
• Feeling of something in the eye (foreign body sensation) — usually temporary

Serious Side Effects (less common — seek medical help immediately):

• Raised intraocular pressure (IOP) — one of the most important risks of Dexamethasone eye drops. Raised eye pressure can develop silently without symptoms and, if undetected, can damage the optic nerve and cause permanent vision loss. Your doctor will monitor your eye pressure regularly during treatment — report any eye pain, headache, or visual changes immediately
• Posterior Subcapsular Cataract Formation — prolonged steroid eye drop use can cause a specific type of cataract to develop at the back of the eye lens. This risk increases significantly with long-term or repeated courses — another reason why these drops must never be used beyond the prescribed duration
• Steroid-Induced Glaucoma — a serious and potentially permanent condition caused by prolonged steroid use raising eye pressure — regular monitoring of eye pressure is essential
• Worsening or spreading of viral infection — if Herpes simplex or another viral eye infection is present or reactivates, Dexamethasone can cause rapid and serious worsening — stop the drops and seek urgent eye specialist care
• Corneal perforation — in patients with thin corneas or pre-existing corneal disease, prolonged steroid use can rarely lead to corneal thinning and perforation — report any sudden severe eye pain immediately
• Fungal superinfection — prolonged antibiotic-steroid use can allow fungal organisms to overgrow — signs include new discharge, pain, or visual changes after initial improvement
• Allergic reaction to Tobramycin — eyelid swelling, intense itching, conjunctival redness worsening after starting treatment — stop the drops and consult your doctor
• Severe allergic reaction — sudden widespread rash, swelling of the face or throat, difficulty breathing — seek emergency help immediately
• Delayed wound healing — steroid use after eye injury or surgery can slow the healing process — report any unusual discharge or pain

If you notice any serious side effects, stop using the drops immediately and seek urgent medical attention from an eye specialist or go to the nearest hospital emergency.

Drug Interactions

Eyebradex Eye Drops are applied directly to the eye surface and systemic absorption is minimal. However the following interactions and considerations are important:

Always inform your doctor and eye specialist about all medicines, eye preparations, vitamins, or supplements currently being used.

Storage Instructions

• Store below 25°C in a cool, dry place
• Keep away from direct sunlight and excessive heat
• Do not refrigerate or freeze the eye drops
• Keep out of reach of children (بچوں کی پہنچ سے دور رکھیں)
• Do not use after the expiry date printed on the bottle or outer box
• Keep the bottle tightly closed after each use to prevent contamination
• Shake well before each use — this is a suspension and the medicine must be evenly mixed before application
• Discard the bottle 4 weeks after first opening — do not continue to use beyond this period even if liquid remains
• Do not use if the suspension appears permanently settled and cannot be resuspended by shaking, or if it changes colour

Frequently Asked Questions (FAQs)

 What is Eyebradex Eye Drops used for?

Eyebradex Eye Drops are used to treat inflammatory eye conditions where bacterial infection is present or where there is a significant risk of infection developing. Tobramycin kills the bacteria responsible for or threatening the infection, while Dexamethasone reduces the redness, swelling, pain, and inflammatory response in the eye. They are commonly used after eye surgery, for corneal injuries, and for severe eye allergies with secondary bacterial involvement.

 Why must I shake Eyebradex Eye Drops before use?

 Eyebradex is formulated as an ophthalmic suspension — meaning the active ingredients, particularly Dexamethasone, are suspended as tiny particles within the liquid rather than being fully dissolved. If the bottle is not shaken before use, the medicine settles at the bottom and you may apply a drop containing very little active ingredient — giving inadequate treatment. Shaking the bottle mixes the suspension evenly so that every drop contains the correct dose of both Tobramycin and Dexamethasone.

 Can steroid eye drops damage my eyes if used for too long?

Yes — this is one of the most important safety points about Eyebradex. Prolonged use of Dexamethasone eye drops can cause two serious and potentially permanent complications. The first is raised intraocular pressure — where pressure builds up inside the eye and can damage the optic nerve, leading to glaucoma and permanent vision loss. The second is posterior subcapsular cataract — a specific type of lens clouding that develops with long-term steroid use. Both risks increase significantly with duration of use. This is why Eyebradex must never be used for longer than your doctor has prescribed and why your doctor will monitor your eye pressure during treatment.

 Can I wear contact lenses while using Eyebradex Eye Drops?

No. Contact lenses must be removed before applying Eyebradex Eye Drops and must not be worn during the entire treatment course. The preservatives in eye drops can be absorbed by soft contact lenses and accumulate to levels that cause eye irritation or damage the lens material. Additionally, wearing contact lenses during an active eye infection or inflammation is not recommended as it can worsen the condition. Ask your doctor when it is safe to resume contact lens wear after completing your treatment.

 What should I do if I accidentally put too many drops in my eye?

If you accidentally apply more drops than prescribed, gently rinse the eye with clean water or sterile saline to wash out the excess. Do not panic — a single extra drop is unlikely to cause serious harm. However, if you regularly use more drops than prescribed, the risk of steroid-related side effects increases. If you experience any unusual eye pain, sudden vision changes, or significant discomfort after accidental overdose, contact your doctor or eye specialist promptly.

 Why can Eyebradex Eye Drops not be used for viral eye infections?

Dexamethasone is a steroid that works by suppressing the immune response in the eye. While this is beneficial for controlling excessive inflammation, it is dangerous when a viral infection is present — particularly Herpes simplex keratitis. The immune system is normally essential for fighting viral infections. By suppressing immunity, Dexamethasone allows the virus to replicate and spread much more rapidly — potentially causing severe corneal damage, deep ulceration, and in serious cases permanent vision loss. This is why your doctor must carefully examine your eye and rule out any viral infection before prescribing steroid-containing eye drops.

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⚕️ Medical Disclaimer: This product description is for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified doctor or pharmacist before starting, stopping, or changing any medication. This product is a prescription medicine — it must only be used under the supervision of a licensed healthcare professional — preferably a qualified eye specialist (ophthalmologist).

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DRAP Registered | Prescription Required (Rx) | For external use in the eye only | Shake well before use | Keep away from children