Drug Class: Non-Steroidal Anti-Inflammatory Drug (NSAID) | Form: Tablet | Prescription Status: Prescription-Only (Rx) — DRAP Registered
What is Calgesic 500mg?
Calgesic 500mg is a prescription NSAID tablet containing Naproxen 500mg, used to relieve moderate to severe pain and reduce inflammation (درد اور سوجن) associated with arthritis, musculoskeletal conditions, menstrual cramps, and migraine. Naproxen belongs to the propionic acid class of NSAIDs and works by blocking the enzymes responsible for producing prostaglandins, the chemicals in the body that cause pain, swelling, and fever. Compared to shorter-acting NSAIDs, Naproxen provides longer-lasting pain relief, often requiring fewer doses throughout the day.
What is Calgesic 500mg Used For?
Arthritis and Joint Pain: Treats pain, swelling, and stiffness associated with rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and acute gout. Musculoskeletal Disorders: Relieves backache, sprains, strains, and tendonitis caused by injury or overuse. Menstrual Pain (Dysmenorrhea): Reduces cramping and discomfort associated with painful periods. Post-Operative Pain: Manages pain and inflammation following surgical procedures. Migraine: Helps relieve migraine headache pain when taken at the onset of an attack.
How Does Calgesic 500mg Work?
Naproxen inhibits cyclooxygenase (COX-1 and COX-2) enzymes, which the body uses to produce prostaglandins. Prostaglandins are responsible for causing pain, inflammation, and fever at sites of injury or disease. By reducing prostaglandin production, Calgesic 500mg provides effective and sustained relief from pain and swelling. Its longer half-life compared to some other NSAIDs means it stays active in the body for a longer period, providing more sustained pain control.
Dosage and Administration
| Situation | Dose | Frequency |
|---|---|---|
| Arthritis and joint pain | 500mg | Twice daily |
| Acute gout | 750mg initially, then 250mg | Every 8 hours as directed |
| Menstrual pain | 500mg initially, then 250mg | Every 6 to 8 hours as needed |
| As prescribed | Follow doctor's instructions | Do not exceed prescribed dose |
Take with food or milk to reduce stomach upset. Swallow whole with a full glass of water. Use the lowest effective dose for the shortest time necessary.
Active Ingredient
| Ingredient | Role |
|---|---|
| Naproxen 500mg | NSAID — inhibits COX enzymes to reduce prostaglandin production, relieving pain and inflammation |
Who Should NOT Use Calgesic 500mg?
Do not use if you have a known allergy to Naproxen, Aspirin, or any other NSAID. Tell your doctor if you have a history of stomach ulcers, kidney disease, liver disease, heart disease, or bleeding disorders. Avoid use in the third trimester of pregnancy. Inform your doctor if you are breastfeeding or taking blood-thinning medicines.
Side Effects
Common: Nausea, stomach upset, heartburn, headache, dizziness, constipation. Serious (seek immediate help): Signs of stomach bleeding including black or bloody stools or severe stomach pain. Signs of kidney or liver problems including swelling, dark urine, or yellowing of skin. Chest pain or shortness of breath. Severe allergic reaction including facial swelling or difficulty breathing.
Storage
Store below 30°C in a dry place away from direct sunlight. Keep out of reach of children (بچوں کی پہنچ سے دور رکھیں). Do not use after the expiry date.
Frequently Asked Questions
Should I take Calgesic 500mg with food?
Yes. Always take Calgesic 500mg with food, milk, or a full glass of water. Naproxen can irritate the stomach lining, and taking it with food significantly reduces the risk of nausea, heartburn, and stomach discomfort.
How is Calgesic 500mg different from Ibuprofen?
Both Naproxen and Ibuprofen are NSAIDs that relieve pain and inflammation. Naproxen 500mg has a longer duration of action, typically lasting 8 to 12 hours compared to 4 to 6 hours for standard Ibuprofen doses. This means fewer daily doses are needed for ongoing pain conditions. Your doctor will advise which NSAID is most suitable for your condition.
Medical Disclaimer: This description is for informational purposes only and does not replace professional medical advice. Always follow your doctor's prescription and consult your pharmacist for personal guidance.
DRAP Registered | Prescription Required (Rx) | Pain and Inflammation | NSAID