Drug Class: Broad-Spectrum Penicillin + Beta-Lactamase Inhibitor Combination | Form: Tablet | Prescription Status: Prescription-Only (Rx) — DRAP Registered
What is Calamox 1g?
Calamox 1g is a prescription broad-spectrum antibiotic tablet containing Amoxicillin 875mg and Clavulanic Acid 125mg, manufactured by Bosch Pharmaceuticals. It is used to treat severe and stubborn bacterial infections (بیکٹیریل انفیکشن) of the respiratory tract, urinary tract, skin, ears, sinuses, and bones. Amoxicillin kills bacteria by blocking their cell wall formation. Clavulanic Acid protects Amoxicillin from being broken down by beta-lactamase enzymes that resistant bacteria produce, extending its effectiveness against a broader range of organisms. Calamox 1g is the highest strength in the Calamox range and is reserved for more serious or resistant infections requiring stronger antibiotic cover.
What is Calamox 1g Used For?
Respiratory Tract Infections: Treats community-acquired pneumonia, acute bacterial sinusitis, and acute exacerbations of chronic bronchitis. Ear, Nose, and Throat Infections: Manages severe tonsillitis, sinusitis, and related upper respiratory bacterial infections. Urinary Tract Infections: Treats cystitis and pyelonephritis caused by susceptible bacteria. Skin and Soft Tissue Infections: Manages cellulitis, infected animal bites, and skin abscesses caused by bacteria. Dental Infections: Treats severe dental abscesses with spreading infection. Bone and Joint Infections: Used for osteomyelitis and bacterial joint infections.
How Does Calamox 1g Work?
Amoxicillin belongs to the penicillin class of antibiotics and kills bacteria by binding to penicillin-binding proteins in the bacterial cell wall, preventing the bacteria from completing cell wall synthesis. Without an intact cell wall, bacteria cannot survive. Clavulanic Acid does not have significant antibiotic activity on its own but irreversibly inhibits beta-lactamase enzymes that resistant bacteria produce to destroy Amoxicillin. By protecting Amoxicillin from this degradation, Clavulanic Acid extends its effectiveness against resistant strains including beta-lactamase producing Staphylococcus, E. coli, and Haemophilus influenzae.
Dosage and Administration
| Situation | Dose | Frequency |
|---|---|---|
| Severe respiratory and urinary infections | 1 tablet (1g) | Twice daily |
| Skin, bone, and dental infections | 1 tablet (1g) | Twice daily |
| As prescribed | Follow doctor's instructions | Complete the full course |
Take at the start of a meal to reduce stomach upset and improve absorption. Swallow whole with a full glass of water. Always complete the full prescribed course even if symptoms improve before the course ends.
Active Ingredients
| Ingredient | Role |
|---|---|
| Amoxicillin 875mg | Penicillin antibiotic — kills bacteria by disrupting cell wall synthesis |
| Clavulanic Acid 125mg | Beta-lactamase inhibitor — protects Amoxicillin from bacterial enzyme degradation to broaden its spectrum |
Who Should NOT Use Calamox 1g?
Do not use if you have a known allergy to Amoxicillin, Clavulanic Acid, or any penicillin or cephalosporin antibiotic. Tell your doctor if you have liver disease, kidney problems, or a history of jaundice related to previous Amoxicillin-Clavulanic Acid use. Inform your doctor if you are pregnant or breastfeeding.
Side Effects
Common: Nausea, diarrhea, stomach upset, skin rash, headache, vaginal yeast infection. Serious (seek immediate help): Severe allergic reaction including facial swelling, difficulty breathing, or widespread skin rash. Signs of liver problems including yellowing of skin or eyes and dark urine. Severe diarrhea with blood or mucus which may indicate Clostridioides difficile infection.
Storage
Store below 25°C in a dry place away from direct sunlight and moisture. Keep out of reach of children (بچوں کی پہنچ سے دور رکھیں). Do not use after the expiry date. Store in original packaging.
Frequently Asked Questions
Should I take Calamox 1g with food?
Yes. Always take Calamox 1g at the start of a meal. Taking it with food reduces the risk of nausea and stomach upset, and also improves the absorption of Clavulanic Acid into the bloodstream.
Why must I complete the full course of Calamox 1g?
Stopping the antibiotic early, even when feeling better, allows surviving bacteria to recover and multiply. This increases the risk of the infection returning and contributes to antibiotic resistance. Always finish the full prescribed course as directed by your doctor.
Medical Disclaimer: This description is for informational purposes only and does not replace professional medical advice. Always follow your doctor's prescription and consult your pharmacist for personal guidance.
DRAP Registered | Prescription Required (Rx) | Broad-Spectrum Antibiotic | Manufactured by Bosch Pharmaceuticals