Drug Class: Calcium + Vitamin Combination Nutritional Supplement | Form: Effervescent Oral Tablet | Prescription Status: Available Without Prescription (OTC) — DRAP Registered
What is CaC-1000 Plus Cola Effervescent Tablet?
CaC-1000 Plus Cola is a cola-flavoured effervescent calcium supplement featuring a unique double calcium formula — combining Calcium Lactate Gluconate 1000mg and Calcium Carbonate 327mg to deliver comprehensive calcium supplementation through two complementary calcium sources simultaneously. Calcium Lactate Gluconate provides highly soluble rapidly absorbed calcium in a neutral pH organic salt form while Calcium Carbonate provides additional elemental calcium in a well-established and cost-effective form. Together they deliver a meaningful combined elemental calcium dose supporting bone mineralisation and numerous other calcium-dependent physiological functions. The addition of Vitamin C 500mg, Vitamin D3 400 IU, and Vitamin B6 10mg addresses the essential cofactors required for optimal calcium absorption, utilisation, and immune function — making CaC-1000 Plus a genuinely comprehensive bone and immunity support supplement. The effervescent cola-flavoured tablet dissolves completely in water providing a pleasant fizzy drink that improves compliance particularly in patients who dislike swallowing tablets.
What is CaC-1000 Plus Used For?
- Calcium deficiency — correcting and preventing inadequate dietary calcium intake (کیلشیم کی کمی)
- Bone health and density — supporting skeletal mineralisation and reducing osteoporosis risk (ہڈیوں کی مضبوطی اور گھنت)
- Osteoporosis prevention and management — particularly in postmenopausal women and elderly patients (ہڈیوں کی کمزوری کی روک تھام)
- Immune system support — high-dose Vitamin C 500mg and Vitamin D3 provide comprehensive immune enhancement (قوت مدافعت کو مضبوط کرنا)
- Pregnancy and breastfeeding calcium requirements — meeting increased maternal calcium demands (حمل اور دودھ پلانے میں کیلشیم کی ضرورت)
- Fatigue and muscle weakness from calcium or Vitamin deficiency (تھکاوٹ اور کمزوری میں کمی)
- Muscle cramps — calcium is essential for normal muscle contraction and relaxation (پٹھوں کی اینٹھن میں کمی)
- Growth support in adolescents — peak bone mass development during teenage years
- Post-menopausal bone loss — oestrogen decline accelerates calcium loss requiring supplementation
How Does it Work?
Each component addresses calcium metabolism and bone health through distinct mechanisms. Calcium Lactate Gluconate 1000mg is a highly water-soluble organic calcium salt that dissolves completely in the effervescent solution — providing ionised calcium that is rapidly absorbed in the upper gastrointestinal tract without requiring gastric acid for solubilisation, making it particularly effective for patients with reduced stomach acid. Calcium Carbonate 327mg provides additional elemental calcium — absorbed most efficiently in an acidic gastric environment — complementing the pH-independent absorption of Calcium Lactate Gluconate. Vitamin D3 400 IU activates Vitamin D receptors in the intestinal wall — upregulating calcium transport proteins that actively increase calcium absorption from the gastrointestinal tract, and stimulating osteocalcin production for bone mineralisation. Without adequate Vitamin D3, even high calcium intake is poorly absorbed and ineffective. Vitamin C 500mg provides powerful antioxidant protection, supports collagen synthesis essential for bone matrix formation, and enhances immune cell function. Vitamin B6 10mg supports protein and collagen metabolism — contributing to bone matrix integrity and reducing homocysteine levels that negatively affect bone quality.
Dosage and Administration
⚠️ Always dissolve completely in a full glass of water — approximately 200ml — before drinking. Never swallow the effervescent tablet whole. Drink immediately after complete dissolution. Take with or after a meal for best absorption and tolerability. Do not exceed one tablet daily without medical advice — total daily calcium from all dietary and supplementary sources should not regularly exceed 2500mg.
| Indication | Usual Adult Dose | Frequency | Notes |
|---|---|---|---|
| Calcium deficiency / Bone support | 1 effervescent tablet | Once daily | Dissolved in 200ml water — drink immediately |
| Osteoporosis prevention | 1 effervescent tablet | Once daily | With meal for best absorption |
| Pregnancy / Breastfeeding | 1 effervescent tablet | Once daily | Under obstetrician supervision |
| Immune support / Fatigue | 1 effervescent tablet | Once daily | Morning preferred for energy benefit |
| Adolescent growth support | 1 effervescent tablet | Once daily | With morning or evening meal |
Active Ingredients
| Ingredient | Strength per Tablet | Primary Role |
|---|---|---|
| Calcium Lactate Gluconate | 1000mg | Rapidly soluble organic calcium — pH-independent absorption |
| Calcium Carbonate | 327mg | Additional elemental calcium source |
| Vitamin C (Ascorbic Acid) | 500mg | Immune support, collagen synthesis, antioxidant protection |
| Vitamin D3 (Cholecalciferol) | 400 IU | Calcium absorption regulation and bone mineralisation |
| Vitamin B6 (Pyridoxine) | 10mg | Collagen metabolism and homocysteine reduction |
Who Should NOT Take CaC-1000 Plus?
- Allergy to any ingredient or excipient including effervescent base components
- Hypercalcaemia — already elevated blood calcium levels; additional supplementation dangerous
- Hypervitaminosis D — existing Vitamin D toxicity; do not combine with other high-dose Vitamin D supplements
- Kidney stones — particularly calcium oxalate or calcium phosphate stones; high calcium intake increases recurrence risk
- Severe kidney impairment — impaired calcium excretion causes dangerous accumulation
- Sarcoidosis — increased sensitivity to Vitamin D causing hypercalcaemia
- Certain cancers — some malignancies raise blood calcium; supplementation may worsen hypercalcaemia
- Patients on thiazide diuretics — increased hypercalcaemia risk from calcium supplementation plus thiazide-reduced urinary calcium excretion
- Phenylketonuria (PKU) — check effervescent excipients for Phenylalanine content
- Children under 4 years — adult effervescent formulation not appropriate
Side Effects
CaC-1000 Plus is generally very well tolerated — the effervescent liquid form is significantly better tolerated than calcium tablets or capsules.
Common:
Mild stomach discomfort or bloating — effervescent formula significantly reduces this compared to solid calcium tablets (پیٹ میں ہلکی تکلیف), mild constipation from calcium component — increase water intake throughout the day (ہلکی قبض — پانی زیادہ پیئیں), mild nausea if taken on completely empty stomach (خالی پیٹ متلی — کھانے کے ساتھ لیں), bright yellow urine from Vitamin B6 at higher doses — completely harmless (پیشاب کا پیلا رنگ — بے ضرر).
Serious (Seek medical attention immediately):
Hypercalcaemia from excessive prolonged intake — nausea, vomiting, extreme thirst, frequent urination, confusion, muscle weakness, and kidney pain (فوری ڈاکٹر کو بتائیں), kidney stone symptoms — severe flank pain with blood in urine (گردے کی پتھری — فوری مدد لیں), severe allergic reaction — sudden widespread rash, swelling of face or throat, difficulty breathing (فوری ہسپتال جائیں), signs of Vitamin D toxicity with prolonged use alongside other D supplements — excessive thirst, confusion, and weakness (فوری ڈاکٹر کو بتائیں).
Drug Interactions
| Medicine | Interaction |
|---|---|
| Bisphosphonates (Alendronate, Risedronate) | Calcium dramatically reduces bisphosphonate absorption — take at least 2 hours apart; critical for osteoporosis patients on both |
| Levothyroxine (thyroid medicine) | Calcium significantly reduces Levothyroxine absorption — take at least 4 hours apart |
| Tetracycline / Doxycycline antibiotics | Calcium chelates tetracyclines reducing absorption — take at least 2 hours apart |
| Fluoroquinolone antibiotics (Ciprofloxacin) | Calcium reduces fluoroquinolone absorption — take at least 2 hours apart |
| Thiazide diuretics (Hydrochlorothiazide) | Reduce urinary calcium excretion — combined with supplemental calcium increases hypercalcaemia risk; monitor calcium levels |
| Digoxin | Hypercalcaemia from excessive calcium increases Digoxin toxicity and arrhythmia risk — monitor calcium levels carefully |
| Iron supplements | Calcium competitively inhibits iron absorption — take at least 2 hours apart |
| Corticosteroids (Prednisolone) | Long-term corticosteroids deplete calcium — supplementation particularly important but monitor total intake |
| Other Vitamin D supplements | Avoid combining multiple Vitamin D sources — cumulative toxicity risk; total daily D3 should not exceed 4000 IU without medical monitoring |
| Zinc supplements | Calcium reduces zinc absorption at high doses — take at least 2 hours apart |
Storage:
Store below 25°C in a cool, dry place. Protect from moisture and direct sunlight — effervescent tablets are highly moisture-sensitive and must be kept in original sealed tube. Replace tube cap immediately after removing each tablet. Keep out of reach of children (بچوں کی پہنچ سے دور رکھیں). Do not use after expiry date.
Frequently Asked Questions (FAQs)
Q: Why does CaC-1000 Plus use two different calcium forms rather than a single calcium source?
Calcium Lactate Gluconate and Calcium Carbonate have complementary absorption profiles. Calcium Lactate Gluconate is highly water-soluble and absorbed independently of stomach acid — ideal for patients with reduced gastric acid, elderly patients, and those taking acid-reducing medicines. Calcium Carbonate provides additional elemental calcium most efficiently absorbed with adequate stomach acid. Using both forms ensures calcium absorption occurs across a broader range of gastrointestinal conditions — maximising total calcium delivery regardless of individual gastric acid levels.
Q: Is the effervescent cola-flavoured form of CaC-1000 Plus as effective as regular calcium tablets?
The effervescent form may actually be superior for many patients — dissolved calcium ions in solution are immediately available for intestinal absorption without requiring tablet disintegration or dissolution. The pleasant cola taste dramatically improves compliance — particularly important for osteoporosis patients who must supplement daily for years. Consistent daily compliance ultimately determines supplementation effectiveness — and patients who genuinely enjoy taking their supplement are significantly more likely to maintain consistent long-term use.
Q: Can CaC-1000 Plus be taken by pregnant and breastfeeding women for their increased calcium needs?
Yes, under obstetrician supervision. Pregnancy and breastfeeding dramatically increase calcium requirements — the developing foetus requires substantial calcium for skeletal development and breastfeeding transfers significant calcium into breast milk. CaC-1000 Plus provides a clinically meaningful calcium dose with Vitamin D3 to enhance absorption. However pregnant women should confirm total daily calcium from diet plus supplementation with their obstetrician — excessive calcium supplementation during pregnancy also carries risks and the appropriate dose depends on individual dietary calcium intake.
Medical Disclaimer: This information is for general awareness only and does not replace medical advice. Always consult a qualified doctor or pharmacist before taking any supplement, particularly if you have kidney disease, kidney stones, or are taking prescription medicines.