Drug Class: Combination Antibiotic (Penicillin + Beta-Lactamase Inhibitor) | Form: Film-Coated Tablet | Prescription Status: Prescription Only (Rx) — DRAP Registered
What is Augmentin 375mg Tablets?
Augmentin 375mg is a prescription combination antibiotic tablet used to treat mild to moderate bacterial infections (بیکٹیریل انفیکشن کا علاج). Each tablet contains two active ingredients working together — Amoxicillin 250mg, a broad-spectrum penicillin antibiotic that kills bacteria, and Clavulanic Acid 125mg, a beta-lactamase inhibitor that protects Amoxicillin from being destroyed by resistant bacteria. This combination makes Augmentin effective against many bacteria that would otherwise resist Amoxicillin alone. It must only be used for confirmed or suspected bacterial infections — it does not work against viral infections such as the common cold or flu.
What is Augmentin 375mg Used For?
Augmentin 375mg is prescribed by doctors for the treatment of the following bacterial infections:
- Sinusitis — bacterial infection causing facial pain, blocked nose, and thick nasal discharge (سائنوسائٹس)
- Ear Infections (Otitis Media) — bacterial infection of the middle ear, commonly seen in children (کان کا انفیکشن)
- Chest and Respiratory Infections — including community-acquired pneumonia and acute bronchitis caused by susceptible bacteria
- Urinary Tract Infections (UTIs) — bacterial infections of the bladder and urinary system (پیشاب کی نالی کا انفیکشن)
- Skin and Soft Tissue Infections — bacterial infections of the skin, wounds, and surrounding tissues (جلد کا انفیکشن)
- Tonsillitis and Throat Infections — caused by susceptible strains of bacteria
How Does Augmentin 375mg Work?
Amoxicillin — The Antibiotic: Amoxicillin works by damaging the cell wall of bacteria — causing the bacteria to break apart and die. It is effective against a broad range of common bacteria responsible for respiratory, urinary, ear, and skin infections.
Clavulanic Acid — The Protector: Some bacteria produce an enzyme called beta-lactamase that destroys Amoxicillin before it can work — making the infection resistant to treatment. Clavulanic Acid blocks this enzyme — protecting Amoxicillin and allowing it to kill a much wider range of bacteria effectively, including resistant strains.
Active Ingredients
| Ingredient | Strength | Role |
|---|---|---|
| Amoxicillin (as Amoxicillin Trihydrate) | 250mg per tablet | Broad-spectrum penicillin antibiotic — kills susceptible bacteria by destroying their cell wall |
| Clavulanic Acid (as Potassium Clavulanate) | 125mg per tablet | Beta-lactamase inhibitor — protects Amoxicillin from resistant bacteria enzymes |
Dosage and Administration
Always take Augmentin exactly as prescribed by your doctor. Do not change your dose or stop early without consulting your doctor first.
| Patient Group | Recommended Dose | Frequency |
|---|---|---|
| Adults and children over 12 years | One 375mg tablet | Three times daily (every 8 hours) |
| Children under 12 years | As directed by the doctor — weight-based dosing required | As prescribed |
| Patients with kidney problems | Dose adjustment may be required | As directed by doctor |
Take each tablet with food or at the start of a meal to reduce stomach upset. Always complete the full prescribed course — even if you feel better early. Stopping antibiotics too soon can allow the infection to return and increase the risk of antibiotic resistance.
Who Should NOT Take Augmentin 375mg?
Do not take Augmentin 375mg if you:
- Are allergic to penicillin, amoxicillin, clavulanic acid, or any other beta-lactam antibiotic — tell your doctor before starting treatment
- Have a history of liver problems or jaundice caused by Augmentin or amoxicillin previously
- Have been told by your doctor to avoid this medicine for any reason
Tell your doctor before use if you have kidney disease, liver disease, or are pregnant or breastfeeding — your doctor will assess whether Augmentin is safe and appropriate for you.
Side Effects
Common Side Effects
- Nausea, vomiting, or stomach upset — taking the tablet with food helps reduce these effects
- Diarrhoea — mild and usually settles after completing the course
- Headache
- Skin rash — stop the medicine and contact your doctor if a rash develops
Serious Side Effects — Seek Medical Help Immediately
- Severe allergic reaction (Anaphylaxis) — signs include sudden swelling of the face, lips or throat, difficulty breathing, or severe skin rash — stop the medicine and seek emergency medical help immediately
- Liver problems — signs include yellowing of the skin or eyes (jaundice), dark urine, or persistent stomach pain — consult your doctor promptly
- Severe or persistent diarrhoea — may indicate a serious bowel infection (C. difficile) — stop the medicine and contact your doctor
Drug Interactions
| Medicine | Interaction |
|---|---|
| Warfarin (blood thinner) | Augmentin may increase the blood-thinning effect — INR monitoring required |
| Methotrexate | Augmentin may increase methotrexate toxicity — use with caution under doctor supervision |
| Oral contraceptive pills | Antibiotics may reduce effectiveness — use additional contraceptive precautions during treatment |
| Allopurinol (for gout) | Increased risk of skin rash when taken together |
Always tell your doctor and pharmacist about all medicines, vitamins, and supplements you are currently taking before starting Augmentin.
Storage Instructions
- Store below 25°C in a cool, dry place
- Keep away from direct sunlight and moisture
- Keep out of reach of children (بچوں کی پہنچ سے دور رکھیں)
- Do not use after the expiry date printed on the pack
- Store in the original packaging to protect from light and humidity
Frequently Asked Questions (FAQs)
Q: What is Augmentin 375mg used for?
Augmentin 375mg is a prescription antibiotic used to treat bacterial infections including sinusitis, ear infections, chest infections, urinary tract infections (UTIs), skin infections, and tonsillitis. It contains Amoxicillin 250mg and Clavulanic Acid 125mg — working together to kill bacteria and overcome antibiotic resistance. It does not treat viral infections such as colds or flu.
Q: Can I take Augmentin if I am allergic to penicillin?
No — Augmentin contains Amoxicillin, which belongs to the penicillin family of antibiotics. If you have a known penicillin allergy, you must tell your doctor before taking Augmentin. Your doctor will prescribe a different antibiotic that is safe for you.
Q: Should I complete the full course of Augmentin?
Yes — always complete the full prescribed course even if you feel better after a few days. Stopping antibiotics early allows some bacteria to survive, which can cause the infection to return — and may contribute to antibiotic resistance over time.
Q: Can I take Augmentin with food?
Yes — and it is recommended. Taking Augmentin with food or at the start of a meal significantly reduces the chances of nausea and stomach upset, which are the most common side effects of this antibiotic.
⚕️ Medical Disclaimer: This product description is for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Augmentin is a prescription-only antibiotic — always use it under the supervision of a qualified doctor or pharmacist. Do not self-medicate with antibiotics.
Prescription Only (Rx) | DRAP Registered | Film-Coated Tablet | For oral use only